[1]林守华 张旭 汪银洲 陈兴泳.联合ABCD3评分和头颈CTA评估短暂性脑缺血发作患者近期发生脑梗死的风险[J].内科,2015,(02):139-142.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2015.02.01]
 LIN Shou-hua,ZHANG Xu,WANG Yin-zhou,et al.The clinical value of ABCD3score combined with CTA in identifying transient ischemic attack patients at early risk of cerebral infarction[J].Internal Medicine of China,2015,(02):139-142.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2015.02.01]
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联合ABCD3评分和头颈CTA评估短暂性脑缺血发作患者近期发生脑梗死的风险()
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《内科》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2015年02期
页码:
139-142
栏目:
论著
出版日期:
2015-04-15

文章信息/Info

Title:
The clinical value of ABCD3score combined with CTA in identifying transient ischemic attack patients at early risk of cerebral infarction
文章编号:
1673-7768(2015)02-0139-04
作者:
林守华 张旭 汪银洲 陈兴泳
福建医科大学省立临床学院/福建省立医院神经内科,福州市350001
Author(s):
LIN Shou-hua ZHANG XuWANG Yin-zhou CHEN Xing-yong
Department of Neurology, Provincial Clinical College of Fujian Medical University/the Fujian Provincial Hospital, Fuzhou 350001, China
关键词:
短暂性脑缺血发作脑梗死ABCD3评分CT血管成像
Keywords:
Transient ischemic attack Cerebral infarction ABCD3 score Comouted according to the findings of tomography angiography
分类号:
R 743
DOI:
DOI:10.16121/j.cnki.cn45-1347/r.2015.02.01
文献标志码:
A
摘要:
目的探讨ABCD3评分结合头颈CT血管成像(CTA)预测短暂性脑缺血发作(TIA)后7 d内发生脑梗死的临床价值。方法收集136例TIA患者临床资料和CTA检查结果。按ABCD3评分法进行评分,分为低危(0~3分)、中危(4~5分)、高危(6~9分)三组;按CTA结果分为血管轻度(狭窄<50%)、中度(狭窄50%~69%)、重度(狭窄>70%)狭窄,观察TIA后7 d内脑梗死发生率。结果29例(21.3%)患者在TIA后7 d内发生脑梗死。低危组与中危组、高危组患者脑梗死发生率(分别为10.2%、22.5%、40.5%)比较差异有统计学意义(P<0.05)。中重度狭窄的颅内外动脉狭窄的患者TIA后7 d内脑梗死发生率显著高于轻度动脉狭窄的患者(χ2=27.827,P=0.000)。ABCD3评分≥4分、颅内外动脉狭窄≥50%组患者7 d内脑梗死发生率显著高于ABCD3评分<4分、颅内外动脉狭窄<50%组(P<0.001)。预测TIA 后7 d 内脑梗死风险时,ABCD3评分和颅内外动脉狭窄程度的AUC分别为0.752和0.779(P<0.001)。结论ABCD3评分法是预测TIA后7 d内发生脑梗死的有效方法,进一步结合头颈CTA检查能提高预测的准确性。
Abstract:
ObjectiveTo investigate the clinical value of ABCD3 score combined with CTA in identifying transient ischemic attack (TIA)patients with high risks of cerebral infarction within 7 days. MethodsThe clinical data and CTA findings of 136 patients with TIA were analyzed. Patients were divided into low-risk group (0-3 points), moderate-risk group(4-5 points), high-risk group(6-9 points)and vascular mild group(stenosis<50%), moderate stenosis group(stenosis 50%-69%), severe stenosis group (stenosis>70%)according to ABCD3 score and the results of CTA,respectively.The incidence of cerebral infarction was observed after TIA within 7 days. Results29 patients(21.3%) suffered cerebral infarction after TIA within 7 days. The incidence of cerebral infarction in low-risk group (10.2%) was significantly lower than that of medium-risk group (22.5%) and high-risk group (40.5%) (P<0.05). The incidence of cerebral infarction of artery moderate and severe stenosis group were significantly higher than that of mild stenosis group(χ2=27.827, P=0.000). The incidence of cerebral infarction in moderate-risk group (ABCD3≥4points) and moderate group(artery stenosis≥50%)were significantly higher than that in low-risk group (ABCD3≥3points) and vascular mild group(artery stenosis<50%) (P<0.001).To predict risks of early cerebral infarction in TIA patients within 7 days, the AUC of ABCD3 and intra-and extra-cranial artery stenosis were 0.752 and 0.779 (P<0.001), respectively. ConclusionsABCD3 score is effective to predict risk of cerebral infarction after TIA within 7 days, and the predictive accuracy can be improved by combination of ABCD3 score and the finds of CTA.

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备注/Memo

备注/Memo:
基金项目:福建省自然科学基金面上项目(2014J01401)
更新日期/Last Update: 2015-09-29