[1]黄家财,卢文生.急性胰腺炎患者血浆降钙素原的变化及其意义[J].内科,2012,(05):463-464.
 HUANG Jia-cai,LU Wen-sheng.Predictive value of serum level of procalcitonin on the prognosis of patients with acute pancreatitis[J].Internal Medicine of China,2012,(05):463-464.
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急性胰腺炎患者血浆降钙素原的变化及其意义()
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《内科》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2012年05期
页码:
463-464
栏目:
论著
出版日期:
2012-10-25

文章信息/Info

Title:
Predictive value of serum level of procalcitonin on the prognosis of patients with acute pancreatitis
文章编号:
1673-7768(2012)05-0463-02
作者:
黄家财1卢文生2
广西来宾市中医医院检验科1、内科2,来宾市546100
Author(s):
HUANG Jia-cai1LU Wen-sheng2
1 Department of Laboratory,2 Department of Internal Medicine,Laibin Hospital of Traditional Chinese Medical,Laibin 546100,China
关键词:
降钙素原急性胰腺炎疾病严重程度预测价值
Keywords:
ProcalcitoninAcute pancreatitisSeverity of diseasePredictive value
分类号:
R 576;R 657.51
文献标志码:
B
摘要:
目的探讨血浆降钙素原(PCT)水平对急性胰腺炎(AP)患者预后的预测价值。方法将入选的122例急性胰腺炎患者,根据Ranson评分标准分为轻型胰腺炎组(68例)和重型胰腺炎组(54例),比较两组患者白细胞计数、中性粒细胞比值、血浆淀粉酶、脂肪酶、C反应蛋白(CRP)以及PCT水平。腹部CT检查评估两组患者CT严重指数(CTSI),评估CTSI和血浆PCT水平的相关性。结果(1)与轻型急性胰腺炎患者相比,重型组患者白细胞总数、中性粒细胞比值、血浆淀粉酶、脂肪酶、CRP以及PCT均明显升高,差异具有统计学意义(P<0.05);(2)Spearman相关分析提示CTSI分级与血浆PCT水平呈正相关(r=0.886,P<0.05)。结论检测急性胰腺炎患者血浆PCT水平有利于对患者预后的评估。
Abstract:
ObjectiveTo investigate the predictive value of serum level of procalcitonin (PCT) on the prognosis of patients with acute pancreatitis.Methods122 patients defined as acute pancreatitis were enrolled and assigned into mild (68 patients) and severe (54 patients) groups according to the Ranson criterion.The white blood cell count,ratio of neutrophil,and serum levels of amylase,lipase,C-reactive protein (CRP) and PCT were compared between the two groups.CT scan was applied to evaluate the CT severe index (CTSI) of the two groups and the relationship of CTSI with serum level of PCT were analyzed.Results(1) Compared to the mild group,total number of white blood cell,ratio of neutrophil,and serum levels of amylase,lipase,CRP and PCT were significantly higher in severe group (P<0.05).(2) Exudation,abscess and necrosis of pancreas were worse in severe group than mild group as indicated by the CTSI,and CTSI was positive correlation with serum level of PCT as indicated by Spearman rank correlation analysis (r=0.886,P<0.05).ConclusionIt is beneficial to predict the prognosis of patients with acute pancreatitis by the detection of serum level of PCT.

参考文献/References:

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更新日期/Last Update: 2015-12-30