[1]钟思苗,丁辉,江泽良,等.肾血流超声检测预测高血压患者早期肾损伤的临床价值分析[J].内科,2019,14(02):165-167+132.[doi:10.16121/j.cnki.cn45-1347/r.2019.02.11]
 ZHONG Simiao,DING Hui,JIANG Zeliang,et al.Clinical value of ultrasound test of renal blood flow on predicting early renal injury in hypertensive patients[J].Internal Medicine of China,2019,14(02):165-167+132.[doi:10.16121/j.cnki.cn45-1347/r.2019.02.11]
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肾血流超声检测预测高血压患者早期肾损伤的临床价值分析()
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《内科》[ISSN:1006-6977/CN:61-1281/TN]

卷:
14卷
期数:
2019年02
页码:
165-167+132
栏目:
论著
出版日期:
2019-04-30

文章信息/Info

Title:
Clinical value of ultrasound test of renal blood flow on predicting early renal injury in hypertensive patients
文章编号:
1673-7768(2019)02-0165-04
作者:
钟思苗丁辉江泽良黄春兰吴小文
肇庆市第一人民医院超声医学科,广东省肇庆市526060
Author(s):
ZHONG Simiao DING Hui JIANG Zeliang HUANG Chunlan WU Xiaowen
Department of Ultrasound, the First People′s Hospital of Zhaoqing City, Zhaoqing 526060, China
关键词:
高血压早期肾损伤多普勒超声肾血流
Keywords:
Hypertension Early kidney injury Doppler ultrasound Renal blood flow
分类号:
R 544.1
DOI:
10.16121/j.cnki.cn45-1347/r.2019.02.11
文献标志码:
A
摘要:
目的分析肾血流超声检测预测高血压患者早期肾损伤的临床应用价值。方法选取2015年2月至2018年2月我院收治的高血压早期肾损伤患者60例作为观察组,选取我院同期收治的单纯高血压患者60例作为对照组。对两组患者的肾窦部段动脉(SRA)、肾锥体叶间动脉(IRA)进行肾血流超声检测,比较两组患者SRA、IRA的舒张末期血流速度(Vd)、收缩期最大血流速度(Vs)以及阻力指数(RI);绘制ROC曲线,分析肾血流超声检测预测高血压患者早期肾损伤的临床应用价值。结果两组患者SRA、IRA的Vs比较差异无统计学意义(P>0.05);观察组患者SRA、IRA的Vd显著低于对照组,SRA、IRA的RI显著高于对照组,差异有统计学意义(P<0.05)。根据高血压患者SRA的Vd、RI预测其早期肾损伤的ROC曲线下面积分别为0.662和0.714;根据患者IRA的Vd、RI预测其早期肾损伤的ROC曲线下面积分别为0.622和0.743。结论高血压早期肾损伤患者的肾血管阻力增加,肾内动脉血流速度减缓,根据其SRA、IRA的RI预测早期肾损伤具有一定的临床应用价值。临床上可结合患者血肌酐、内生肌酐清除率等生化指标水平对患者早期肾损伤进行评估。
Abstract:
ObjectiveTo analyze the clinical application value of renal blood flow ultrasound test on predicting early renal injury in patients with hypertension. Methods60 hypertensive patients with early renal were selected as observation group and 60 patients with simple hypertension were selected as control group, both were admitted to our hospital from February 2015 to February 2018. Ultrasound of renal blood flow was detected in the segmental renal artery (SRA) and interlobular renal artery (IRA) of the two groups. The end-diastolic blood flow velocity (Vd), maximum systolic blood flow velocity (Vs), and resistance index (RI) of SRA and IRA were compared between the two groups. The ROC curve was drawn and the clinical application value of renal blood flow ultrasound test on predicting early renal injury in hypertensive patients was analyzed. ResultsThere were no significant difference in Vss of SRA and IRA between the two groups (P>0.05). The Vds of SRA and IRA in the observation group were significantly lower than those in the control group, and the RIs of SRA and IRA were significantly higher than those in the control group (P<0.05). According to the Vd and RI of SRA of hypertensive patients, the area under the ROC curve for predicting early kidney injury was 0.662 and 0.714, respectively. According to the Vd and RI of the IRA, the area under the ROC curve for predicting early renal injury was 0.622 and 0.743, respectively. ConclusionRenal vascular resistance increases in hypertensive patients with early renal injury, and blood flow velocity in the renal arteries slows down. Predicting early renal injury based on the RI of SRA and IRA has certain clinical application value. In clinical practice, early renal injury can be assessed by assisting biochemical indicators such as serum creatinine and endogenous creatinine clearance rate.

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更新日期/Last Update: 2019-05-09