[1]吴彦岚,曾伟杰.香砂六君子汤加减辅助治疗减轻乳腺癌化疗患者化疗相关不良反应效果观察[J].内科,2019,14(02):180-183.[doi:10.16121/j.cnki.cn45-1347/r.2019.02.16]
 WU Yanlan,ZENG Weijie.Effect observation of modified Xiangsha Liujunzi Decoction adjuvant therapy on chemotherapy-related adverse reactions in patients with breast cancer chemotherapy[J].Internal Medicine of China,2019,14(02):180-183.[doi:10.16121/j.cnki.cn45-1347/r.2019.02.16]
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香砂六君子汤加减辅助治疗减轻乳腺癌化疗患者化疗相关不良反应效果观察()
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《内科》[ISSN:1006-6977/CN:61-1281/TN]

卷:
14卷
期数:
2019年02
页码:
180-183
栏目:
论著
出版日期:
2019-04-30

文章信息/Info

Title:
Effect observation of modified Xiangsha Liujunzi Decoction adjuvant therapy on chemotherapy-related adverse reactions in patients with breast cancer chemotherapy
文章编号:
1673-7768(2019)02-0180-04
作者:
吴彦岚曾伟杰
广东省中医院乳腺科,广州市510120
Author(s):
WU Yanlan ZENG Weijie
Department of Breast Diseases, the Traditional Chinese Medicine Hospital of Guangdong Provincial, Guangzhou 510120, China
关键词:
乳腺癌化疗化疗相关不良反应香砂六君子汤
Keywords:
Breast cancer Chemotherapy Chemotherapy-related adverse reactions Xiangsha Liujunzi Decoction
分类号:
R 737.9
DOI:
10.16121/j.cnki.cn45-1347/r.2019.02.16
文献标志码:
A
摘要:
目的探讨香砂六君子汤加减辅助治疗对乳腺癌化疗患者化疗相关不良反应的影响。方法选取2017年1月至2018年12月我院收治的乳腺癌患者80例为研究对象,分为观察组与对照组,每组40例。对照组患者在化疗期间给予托烷司琼治疗,观察组患者在对照组治疗基础上加用香砂六君子汤加减治疗。比较两组患者化疗期间的毒副反应及严重程度;比较化疗前后两组患者的生活质量(躯体状况、社会/家庭状况、情感状况、功能状况、附加关注)评分。结果观察组患者化疗期间恶心呕吐、白细胞计数下降的严重程度明显轻于对照组,差异有统计学意义(P<0.05)。化疗第10天,两组患者的躯体状况、社会/家庭状况、情感状况评分均显著提高,观察组患者这三个维度的评分均显著高于对照组,差异有统计学意义(P<0.05)。结论香砂六君子汤加减辅助治疗可显著减轻乳腺癌化疗患者化疗期间的毒副反应,明显提高患者的生活质量,具有较高的临床应用价值。
Abstract:
ObjectiveTo explore the effect of modified Xiangsha Liujunzi Decoction on chemotherapy-related adverse reactions in patients with breast cancer chemotherapy. Methods80 patients with breast cancer admitted to our hospital from January 2017 to December 2018 were enrolled and divided into observation group and control group, with 40 cases in each group. Patients in the control group were treated with tropisetron during chemotherapy. Patients in the observation group were treated with modified Xiangsha Liujunzi Decoction on the basis of the treatment of the control group. The symptoms and severity of toxic side effects during chemotherapy in the two groups were compared. The quality of life (physical status, social/family status, emotional status, functional status, additional attention) scores of the two groups before and after chemotherapy were compared. ResultsThe severity of nausea and vomiting and the decrease of white blood cell count in the observation group during chemotherapy were significantly less than that in the control group, and the difference was statistically significant (P<0.05). On the 10th day of chemotherapy, the physical status, social/family status, and emotional status scores of the two groups were significantly improved, and the scores of these three dimensions in the observation group were significantly higher than the control group, and the difference was statistically significant (P<0.05). ConclusionModified Xiangsha Liujunzi Decoction can significantly reduce the toxic side effects during chemotherapy in patients with breast cancer chemotherapy, and significantly improve the life quality of patients. It has high clinical application value.

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更新日期/Last Update: 2019-05-09