[1]王晓玲,李宝红,尉家森,等.经鼻高流量氧疗对急性呼吸衰竭患者血气分析结果和血流动力学的影响[J].内科,2019,14(05):529-531+611.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2019.05.06]
 WANG Xiaoling,LI Baohong,WEI Jiasen,et al.Effect of high-flow nasal cannula on blood gas analysis and hemodynamics in patients with acute respiratory failure[J].Internal Medicine of China,2019,14(05):529-531+611.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2019.05.06]
点击复制

经鼻高流量氧疗对急性呼吸衰竭患者血气分析结果和血流动力学的影响()
分享到:

《内科》[ISSN:1006-6977/CN:61-1281/TN]

卷:
14卷
期数:
2019年05
页码:
529-531+611
栏目:
论著
出版日期:
2019-10-31

文章信息/Info

Title:
Effect of high-flow nasal cannula on blood gas analysis and hemodynamics in patients with acute respiratory failure
文章编号:
1673-7768(2019)05-0529-04
作者:
王晓玲1李宝红1尉家森1王玮1王立虎2
1 河西学院附属张掖人民医院呼吸科;2 甘州区人民医院感染科,甘肃省张掖市734000
Author(s):
WANG Xiaoling1 LI Baohong1 WEI Jiasen1 WANG Wei1 WANG Lihu2
1 Department of Respiratory, Zhangye People′s Hospital Affiliated to Hexi University; 2 Department ofInfection, Ganzhou District People′s Hospital, Zhangye 734000, Gansu province, China
关键词:
急性呼吸衰竭经鼻高流量氧疗血气分析血流动力学
Keywords:
Acute respiratory failure High-flow nasal cannula Blood gas analysis Hemodynamics
分类号:
R 563.8
DOI:
DOI:10.16121/j.cnki.cn45-1347/r.2019.05.06
文献标志码:
A
摘要:
目的探讨经鼻高流量氧疗对急性呼吸衰竭患者血气分析结果和血流动力学的影响。方法选择2017年1月至2019年1月我院收治的急性呼吸衰竭患者82例为研究对象,采用随机数字表法分为对照组与观察组,每组41例。对照组患者采用常规面罩氧疗法治疗,观察组患者采用经鼻高流量氧疗法治疗,每天氧疗8 h以上,连续治疗2~3 d。比较两组患者治疗前(治疗前1 d)与治疗后(治疗后24 h)的血气分析结果、血流动力学指标、住ICU时间、住院时间以及不良反应发生情况。结果治疗前,两组患者的动脉氧分压(PaO2)、动脉二氧化碳分压(PaCO2)、心率、经皮氧饱和度(SpO2)和呼吸频率比较差异无统计学意义(P>0.05)。治疗后,两组患者的PaO2均显著升高,PaCO2均显著降低,观察组的PaO2高于对照组, PaCO2低于对照组;两组患者的心率、呼吸频率均显著降低,SpO2均显著升高,观察组的心率、呼吸频率低于对照组,而SpO2高于对照组,差异有统计学意义(P<0.05)。观察组患者的住ICU时间和住院时间短于对照组,差异有统计学意义(P<0.05)。治疗期间观察组患者的不良反应发生率(2.44%)显著低于对照组(21.95%),差异有统计学意义(P<0.05)。结论经鼻高流量氧疗治疗急性呼吸衰竭患者临床效果良好,可有效改善患者的血气分析结果和血流动力学指标,减少并发症的发生,促进患者康复。
Abstract:
ObjectiveTo investigate the effect of high-flow nasal cannula on blood gas analysis and hemodynamics in patients with acute respiratory failure. MethodsA total of 82 patients with acute respiratory failure admitted to our hospital from January 2017 to January 2019 were selected as the objects, and were divided into control group and observation group in accordance with random number table method, with 41 cases in each group. The control group received conventional mask oxygen therapy, while the observation group received the treatment of high-flow nasal cannula, with oxygen therapy for more than 8 hours per day, and continuous treatment for 2 to 3 days. Blood gas analysis results, hemodynamic indexes, length of ICU stays, hospital stays, and occurrence of adverse reactions before treatment (1 day before treatment) and after treatment (24 hours after treatment) were compared between the two groups. ResultsBefore treatment, there was no statistically significant difference of comparison in partial arterial oxygen pressure (PaO2), partial pressure of carbon dioxide in arterial blood (PaCO2), heart rate, percutaneous oxygen saturation (SpO2) and respiratory rate between the two groups (P>0.05). After treatment, PaO2 in both groups was significantly increased, while PaCO2 was significantly decreased. PaO2 of the observation group was higher than that of the control group, whereas PaCO2 was lower than that of the control group. The heart rate and respiratory rate in both groups were significantly decreased, whereas SpO2 was significantly increased. The heart rate and respiratory rate of the observation group were lower than those of the control group, while SpO2 was higher than that of the control group, with statistically significant difference (P<0.05). The length of ICU stays and hospital stays in the observation group were shorter than those of the control group. The difference was statistically significant (P<0.05). The incidence of adverse reactions was significantly lower in the observation group (2.44%) than in the control group (21.95%), with statistically significant difference (P<0.05). ConclusionHigh-flow nasal cannula has a good clinical effect on acute respiratory failure. It can effectively improve the blood gas analysis results and hemodynamics indexes, reduce the incidence of complications, and promote a recovery of patients.

相似文献/References:

[1]刘开林.慢性阻塞性肺病并发急性呼吸衰竭的危险因素分析[J].内科,2014,(03):278.
 LIU Kai-lin.Analysis of risk factors of chronic obstructive pulmonary disease combined with acute respiratory failure[J].Internal Medicine of China,2014,(05):278.
[2]李燕玲.恙虫病患者并发急性呼吸衰竭的ICU护理[J].内科,2010,(06):655.
 [J].Internal Medicine of China,2010,(05):655.

更新日期/Last Update: 2019-11-01