[1]蔡晓,黄富娟,罗建君.疏风清热汤治疗急性咽炎患者的疗效及对炎性因子水平的影响[J].内科,2019,14(05):545-547+550.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2019.05.11]
 CAI Xiao,HUANG Fujuan,LUO Jianjun.Effect of Shufeng Qingre decoction on acute pharyngitis and its influence on inflammatory factor level[J].Internal Medicine of China,2019,14(05):545-547+550.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2019.05.11]
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疏风清热汤治疗急性咽炎患者的疗效及对炎性因子水平的影响()
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《内科》[ISSN:1006-6977/CN:61-1281/TN]

卷:
14卷
期数:
2019年05
页码:
545-547+550
栏目:
论著
出版日期:
2019-10-31

文章信息/Info

Title:
Effect of Shufeng Qingre decoction on acute pharyngitis and its influence on inflammatory factor level
文章编号:
1673-7768(2019)05-0545-04
作者:
蔡晓黄富娟罗建君
肇庆市第一人民医院中医科,广东省肇庆市526000
Author(s):
CAI Xiao HUANG Fujuan LUO Jianjun
Department of Traditional Chinese Medicine, the First People′s Hospital of Zhaoqing, Zhaoqing 526000, China
关键词:
急性咽炎疏风清热汤炎性因子
Keywords:
Acute pharyngitis Shufeng Qingre decoction Inflammatory factor
分类号:
R 766
DOI:
DOI:10.16121/j.cnki.cn45-1347/r.2019.05.11
文献标志码:
A
摘要:
目的探讨疏风清热汤治疗急性咽炎患者的疗效及对炎性因子水平的影响。方法选取2019年1~6月我院收治的急性咽炎患者153例为研究对象,采用随机数字表法分为观察组(76例)和对照组(77例)。对照组患者选用西瓜霜润喉片进行治疗;观察组患者选用疏风清热汤进行治疗。治疗1个月后,观察比较两组患者的临床疗效;检测比较两组患者治疗前后的肿瘤坏死因子-α(TNF-α)、白细胞介素-1(IL-1)、白细胞介素-2(IL-2)、白细胞介素-6(IL-6)水平;观察比较两组患者治疗期间的不良反应发生情况。结果治疗1个月,观察组患者的治疗总有效率(89.47%)显著高于对照组(75.32%),差异有统计学意义(P<0.05);两组患者的TNF-α、IL-1、IL-6水平均显著降低,IL-2水平显著升高,观察组患者的TNF-α、IL-1、IL-6水平显著低于对照组,IL-2水平显著高于对照组,差异有统计学意义(P<0.05)。治疗期间,两组患者的不良反应发生率比较差异无统计学意义(P>0.05)。结论疏风清热汤治疗急性咽炎患者临床效果显著,能显著降低患者的炎性因子水平,具有较高的临床应用价值。
Abstract:
ObjectiveTo explore the effect of Shufeng Qingre decoction in patients with acute pharyngitis and the influence on the level of inflammatory factor. MethodsA total of 153 patients with acute pharyngitis admitted to our hospital from January to June 2019 were enrolled as the objects. They were divided into observation group (76 cases) and control group (77 cases) in accordance with random number table method. The control group were treated with Watermelon Frost Lozenges, whereas the observation group were treated with Shufeng Qingre decoction. After 1 month of treatment, the clinical therapeutic effects of the two groups were observed and compared. The tumor necrosis factor-α (TNF-α), interleukin-1 (IL-1), interleukin-2 (IL-2), and interleukin-6 (IL-6) levels between the two groups were detected and compared before and after treatment. The occurrence of adverse reactions between the two groups was observed and compared during the treatment. ResultsAfter 1 month of treatment, the total effective rate of treatment in the observation group (89.47%) was significantly higher than that in the control group (75.32%), with statistically significant difference (P<0.05). The levels of TNF-α, IL-1 and IL-6 were significantly decreased in both groups, whereas IL-2 level was significantly increased. The levels of TNF-α, IL-1 and IL-6 in the observation group were significantly lower than those in the control group, while the level of IL-2 was significantly higher than that of the control group. The difference was statistically significant (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups during treatment (P>0.05). ConclusionShufeng Qingre decoction has a significant clinical effect in the treatment of patients with acute pharyngitis. It can significantly reduce the level of inflammatory factor, and has a high clinical applicable value.
更新日期/Last Update: 2019-11-01