[1]陈惠文,黄树稳,童飞,等.南宁地区0~14岁过敏性疾病患儿7 227例过敏原检测分析▲[J].内科,2019,14(06):640-643.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2019.06.04]
 CHEN Huiwen,HUANG Shuwen,TONG Fei,et al.Allergen detection analysis of 7227 children aged 0-14 with allergic diseases in Nanning area[J].Internal Medicine of China,2019,14(06):640-643.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2019.06.04]
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南宁地区0~14岁过敏性疾病患儿7 227例过敏原检测分析▲()
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《内科》[ISSN:1006-6977/CN:61-1281/TN]

卷:
14卷
期数:
2019年06
页码:
640-643
栏目:
论著
出版日期:
2019-12-30

文章信息/Info

Title:
Allergen detection analysis of 7227 children aged 0-14 with allergic diseases in Nanning area
文章编号:
1673-7768(2019)06-0640-04
作者:
陈惠文黄树稳童飞黄菊莲
南宁市妇幼保健院儿科,广西南宁市530012
Author(s):
CHEN Huiwen HUANG Shuwen TONG Fei HUANG Julian
Department of Pediatrics, Nanning Maternal & Child Health Hospital, Nanning 530012, Guangxi, China
关键词:
过敏性疾病儿童过敏原检测
Keywords:
Allergic disease Child Allergen detection
分类号:
R 593;R 725
DOI:
DOI:10.16121/j.cnki.cn45-1347/r.2019.06.04
文献标志码:
A
摘要:
目的了解广西南宁地区0~14岁过敏性疾病患儿的主要过敏原种类,为提高患儿临床症状控制效果、改善预后,预防过敏性疾病的发生提供参考。方法选择2014年10月至2017年6月在广西南宁市妇幼保健院门诊及住院治疗的0~14岁过敏性疾病患儿7227例作为研究对象,采用酶联免疫法、过敏原特异性IgE抗体检测试剂盒和过敏原检测系统,对患儿血清总IgE及吸入性和食入性过敏原特异性IgE水平进行检测分析。结果过敏性疾病患儿的总IgE阳性率为78.34%,男患儿总IgE阳性率为80.20%,女患儿总IgE阳性率为74.81%。不同年龄过敏性疾病患儿的主要吸入性、食入性过敏原并不相同,呼吸系统、五官及皮肤过敏患儿的主要吸入性过敏原均为尘螨组合,呼吸系统、五官、皮肤及消化系统过敏患儿的主要食入性过敏原均为牛奶。结论对于南宁地区过敏性疾病患儿来说,尘螨是最需避免接触的最主要吸入性过敏原。不论是吸入还是进食过敏原,都容易导致患儿出现呼吸系统、五官、皮肤及消化系统症状。对过敏性疾病患儿完善过敏原检测,对于提高患儿临床症状控制效果、改善预后和预防再发具有重要的意义。
Abstract:
ObjectiveTo understand the main types of allergens in children aged 0-14 with allergic diseases in Nanning area of Guangxi, so as to provide a reference for improving the clinical symptoms control effect, improving the prognosis, and preventing the occurrence of allergic diseases. MethodsA total of 7227 children aged 0-14 with allergic diseases treated in the Department of Outpatient and hospitalized in Nanning Maternal & Child Health Hospital from October 2014 to June 2017 were selected as the research subjects. The serum total IgE and inhaled and ingested allergen-specific IgE levels in children were detected and analyzed using enzyme-linked immunoassay, allergen-specific IgE antibody detection kit, and allergen detection system. ResultsThe total positive rate of IgE in children with allergic diseases was 78.34%, of which male children with 80.20% and female children with 74.81%. The main inhaled and ingested allergens in children with allergic diseases were different at different ages. The main inhaled allergens of respiratory system, five sense organs and skin allergy in children were dust mite combinations. The major ingested allergens of respiratory, five sense organs, skin and digestive allergy in children were milk. ConclusionIn allusion to the children with allergic diseases in Nanning area, dust mites are the major inhaled allergens that need to be avoided. It is easy to cause symptoms of respiratory system, five sense organs, skin and digestive system in children, whatever the allergens belong to inhalation or ingestion. It is of crucial significance for improving the control effect of clinical symptoms, improving prognosis and preventing the re-occurrence by perfecting allergens detection in children with allergic disease.

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备注/Memo

备注/Memo:
▲基金项目:南宁市科学研究与技术开发计划项目(20163344)
更新日期/Last Update: 2019-12-31