[1]马垒垒,陈访,王瑾.益气活血化痰通络方治疗对脑梗死患者血流动力学、血液流变学及颈动脉粥样硬化的影响[J].内科,2019,14(06):661-664.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2019.06.10]
 MA Leilei,CHEN Fang,WANG Jin.Effect of Yiqi Huoxue Huatan Tongluo recipe on hemodynamics, hemorheology and carotid atherosclerosis in patients with cerebral infarction[J].Internal Medicine of China,2019,14(06):661-664.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2019.06.10]
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益气活血化痰通络方治疗对脑梗死患者血流动力学、血液流变学及颈动脉粥样硬化的影响()
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《内科》[ISSN:1006-6977/CN:61-1281/TN]

卷:
14卷
期数:
2019年06
页码:
661-664
栏目:
论著
出版日期:
2019-12-30

文章信息/Info

Title:
Effect of Yiqi Huoxue Huatan Tongluo recipe on hemodynamics, hemorheology and carotid atherosclerosis in patients with cerebral infarction
文章编号:
1673-7768(2019)06-0661-04
作者:
马垒垒陈访王瑾
河南省叶县人民医院中医内科,河南叶县467200
Author(s):
MA Leilei CHEN Fang WANG Jin
Department of Traditional Chinese Medicine, Yexian People′s Hospital in Henan Province, Yexian 467200, China
关键词:
脑梗死益气活血化瘀通络方血流动力学血液流变学颈动脉粥样硬化
Keywords:
Cerebral infarction Yiqi Huoxue Huayu Tongluo recipe Hemodynamics Hemorheology Carotid atherosclerosis
分类号:
R 543;R 74
DOI:
DOI:10.16121/j.cnki.cn45-1347/r.2019.06.10
文献标志码:
A
摘要:
的探讨益气活血化痰通络方治疗对脑梗死患者血流动力学、血液流变学及颈动脉粥样硬化的影响。方法选取2016年5月至2018年5月我院收治的脑梗死患者70例作为研究对象,按随机数表法分成对照组与观察组,每组35例。对照组患者给予常规西医治疗,观察组患者在对照组治疗的基础上加用益气活血化痰通络方治疗。比较两组患者的临床疗效、血流动力学、血液流变学、颈动脉内膜中层厚度(IMT)及颈动脉斑块面积的变化情况。结果治疗1个月,观察组患者的治疗总有效率(97.14%)显著高于对照组(77.14%),差异有统计学意义(P<0.05)。治疗1个月后,两组患者双侧大脑血流的最大峰值流速(Vs)、平均血流速度(Vm)均显著升高,观察组患者的水平显著高于对照组;两组患者的血管阻力指数(RI)、搏动指数(PI)均显著降低,观察组患者的水平显著低于对照组,差异有统计学意义(P<0.05);两组患者的全血黏度、纤维蛋白原水平、红细胞比容均显著降低,观察组患者的水平显著低于对照组,差异有统计学意义(P<0.05);两组患者的颈动脉IMT与颈动脉斑块面积均显著减小,观察组患者的颈动脉IMT与颈动脉斑块面积均显著小于对照组,差异有统计学意义(P<0.05)。结论常规西药联合益气活血化瘀通络方治疗,可有效改善脑梗死患者的血流动力学与血液流变学状况,显著减小患者颈动脉内膜中层厚度及颈动脉粥样硬化斑块面积,值得推广应用。
Abstract:
ObjectiveTo investigate the effects of Yiqi Huoxue Huatan Tongluo recipe on hemodynamics, hemorheology and carotid atherosclerosis in patients with cerebral infarction. MethodsA total of 70 patients with cerebral infarction admitted to our hospital from May 2016 to May 2018 were selected as the research subjects, and were divided into control group and observation group according to the random number table method, with 35 cases in each group. Patients in the control group were administered routine Western medicine, based on which Yiqi Huoxue Huatan Tongluo recipe was employed additionally to patients in the observation group. The clinical efficacy, hemodynamics, hemorheology, carotid intima-media thickness (IMT), and the change condition of carotid plaque area of patients were compared between the two groups. ResultAfter a month of treatment, the total effective rate (97.14%) in the observation group was significantly higher than that in the control group (77.14%), and the difference was statistically significant (P<0.05). The maximal peak flow velocity (Vs) and mean blood flow velocity (Vm) of bilateral cerebral blood flow of patients in the two groups significantly increased, and the levels of patients in the observation group were significantly higher than those in the control group. The resistance index (RI), pulsatility index (PI) significantly decreased, and the levels of patients in the observation group were significantly lower than those in the control group, with the statistically significant differences (P<0.05). The blood viscosity, fibrinogen level, and hematocrit of patients in the two groups significantly decreased, and the levels of patients in the observation group were significantly lower than those in the control group, with the statistically significant differences (P<0.05). The carotid arterial IMT and carotid plaque area of patients in the two groups significantly decreased. The carotid arterial IMT and carotid plaque area of the observation group were significantly smaller than those of the control group, with the statistically significant differences (P<0.05). ConclusionRoutine Western medicine combined with Yiqi Huoxue Huayu Tongluo recipe can effectively improve the conditions of hemodynamics and hemorheology in patients with cerebral infarction, and significantly reduce the carotid intima-media thickness and carotid atherosclerotic plaque area, for it is worth promoting and applying.

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更新日期/Last Update: 2020-01-03