[1]张潭军,肖醒香,金宁.连续性血液净化对ICU脓毒症患者血清LA、PCT、CRP水平以及预后的影响▲[J].内科,2020,15(01):14-16.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2020.01.05]
 ZHANG Tanjun,XIAO Xingxiang,JIN Ning.Effect of continuous blood purification on serum LA, PCT, CRP levels and prognosis in ICU patients with sepsis[J].Internal Medicine of China,2020,15(01):14-16.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2020.01.05]
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连续性血液净化对ICU脓毒症患者血清LA、PCT、CRP水平以及预后的影响▲()
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《内科》[ISSN:1006-6977/CN:61-1281/TN]

卷:
15卷
期数:
2020年01
页码:
14-16
栏目:
论著
出版日期:
2020-03-31

文章信息/Info

Title:
Effect of continuous blood purification on serum LA, PCT, CRP levels and prognosis in ICU patients with sepsis
文章编号:
1673-7768(2020)01-0014-03
作者:
张潭军肖醒香金宁
惠州市第六人民医院重症医学科,广东省惠州市516211
Author(s):
ZHANG Tanjun XIAO Xingxiang JIN Ning
Department of Critical Care Medicine, the Sixth People’s Hospital of Huizhou, Huizhou 516211, Guangdong Province, China
Keywords:
Severe sepsis Continuous blood purification Lactic acid Procalcitonin C-reactive protein Prognosis
分类号:
R 631
DOI:
DOI:10.16121/j.cnki.cn45-1347/r.2020.01.05
文献标志码:
A
Abstract:
ObjectiveTo investigate the effect of continuous blood purification on serum lactic acid (LA), procalcitonin (PCT), C-reactive protein (CRP) levels and prognosis in ICU patients with sepsis. MethodsA total of 70 patients with sepsis admitted to our hospital from February 2017 to January 2019 were selected as the research subjects and randomly divided into control group and observation group, with 35 cases in each group. Both groups received routine treatment for severe sepsis, based on which the control group was administered ulinastatin, whereas the observation group with ulinastatin + continuous blood purification treatment. Serum LA, PCT, CRP levels before and after treatment between the two groups were detected and compared. The ICU stays and twenty-eight-day mortality after therapy between the two groups were compared. ResultsBefore treatment, there were no statistically significant differences in serum LA, PCT, and CRP levels between the two groups (P>0.05). After 1 week of treatment, serum LA, PCT, and CRP levels in the two groups decreased significantly, and the levels in the observation group were significantly lower than those in the control group, with statistically significant differences (P<0.05). The ICU stays and twenty-eight-day mortality after therapy in the observation group were lower than those in the control group, with statistically significant differences (P<0.05). ConclusionContinuous blood purification treatment can significantly decrease serum LA, PCT, and CRP levels in ICU patients with sepsis, which can effectively inhibit the inflammatory response, which plays an important role in promoting the recovery of patients and improving prognosis.

备注/Memo

备注/Memo:
▲基金项目:惠州市科技计划项目(2019Y291)
更新日期/Last Update: 2020-04-07