[1]程源,毛海洲,吴萌.内镜下黏膜切除术和内镜黏膜下剥离术治疗早期胃癌患者临床疗效比较分析[J].内科,2020,15(01):45-47+63.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2020.01.15]
 CHENG Yuan,MAO Haizhou,WU Meng.Clinical efficacy of endoscopic mucosal resection and endoscopic submucosal dissection on early gastric cancer: a comparative analysis[J].Internal Medicine of China,2020,15(01):45-47+63.[doi:DOI:10.16121/j.cnki.cn45-1347/r.2020.01.15]
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内镜下黏膜切除术和内镜黏膜下剥离术治疗早期胃癌患者临床疗效比较分析()
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《内科》[ISSN:1006-6977/CN:61-1281/TN]

卷:
15卷
期数:
2020年01
页码:
45-47+63
栏目:
论著
出版日期:
2020-03-31

文章信息/Info

Title:
Clinical efficacy of endoscopic mucosal resection and endoscopic submucosal dissection on early gastric cancer: a comparative analysis
文章编号:
1673-7768(2020)01-0045-04
作者:
程源毛海洲吴萌
中国人民解放军联勤保障部队第988医院开封院区消化内科,河南省开封市475003
Author(s):
CHENG Yuan MAO Haizhou WU Meng
Department of Gastroenterology, The 988th Hospital of the Joint Logistic Support Force of the Chinese People’s Liberation Army in Kaifeng District, Kaifeng 475003, Henan Province, China
关键词:
早期胃癌内镜黏膜下剥离术内镜下黏膜切除术临床疗效
Keywords:
Early gastric cancer Endoscopic submucosal dissection Endoscopic mucosal resection Clinical efficacy
分类号:
R 735
DOI:
DOI:10.16121/j.cnki.cn45-1347/r.2020.01.15
文献标志码:
A
摘要:
目的比较内镜下黏膜切除术(EMR)和内镜黏膜下剥离术(ESD)治疗早期胃癌患者的临床效果。方法选取2015年1月至2017年7月在我院治疗的早期胃癌患者74例,随机分为EMR组(35例)和ESD组(39例),分别采用EMR和ESD进行治疗。比较两组患者的手术时间、术中出血量、住院时间;比较两组患者的病变完整切除率和疼痛VAS评分;比较两组患者的术后并发症及复发情况。结果ESD组患者的术中出血量少于EMR组,住院时间短于EMR组,差异有统计学意义(P<0.05)。ESD组患者的病变完整切除率(92.31%)明显高于EMR组(71.43%),VAS评分明显低于EMR组,差异有统计学意义(P<0.05)。两组患者术后穿孔、狭窄及术后12个月的复发率比较差异均无统计学意义(P>0.05)。结论应用ESD治疗早期胃癌患者比采用EMR治疗具有一定的优势,可减少患者术中出血量,提高病灶完整切除率,减轻患者术后疼痛程度。
Abstract:
ObjectiveTo compare the clinical effects of endoscopic mucosal resection (EMR) with endoscopic submucosal dissection (ESD) in the treatment of patients with early gastric cancer. MethodsA total of 74 patients with early gastric cancer admitted to our hospital from January 2015 to July 2017 were selected and randomly divided into EMR group (35 cases) and ESD group (39 cases), and treated with EMR and ESD respectively. The operation duration, intraoperative bleeding volume, hospital stays, rate of complete resection of lesions, VAS score, postoperative complications and the prevalence of recurrence were compared between the two groups. ResultsCompared to the EMR group, the ESD group yielded less intraoperative bleeding volume, shorter hospital stay, significantly higher rate of complete resection of lesions (92.31% vs. 71.43%), and lower VAS score, with statistically significant differences (P<0.05). There were no statistically significant differences in postoperative perforation and stenosis, as well as the recurrence rate 12 months after operation between the two groups (P>0.05). ConclusionEmploying ESD in the treatment of early gastric cancer has certain advantages compared to EMR, which can reduce intraoperative bleeding volume, improve rate of complete resection of lesions, and alleviate the degree of pain in patients.

相似文献/References:

[1]韦家成.39例早期胃癌的胃镜下特点分析[J].内科,2012,(03):272.
 [J].Internal Medicine of China,2012,(01):272.

更新日期/Last Update: 2020-04-07