ObjectiveTo study the influences of transient intensive insulin therapy on insulin resistance and serum uric acid of newly diagnosed type 2 diabetic patients.Methods36 cases of newly diagnosed type 2 diabetic patients were treated by intensive insulin therapy for 2 weeks.The levels of serum uric acid(UA),fasting plasma glucose(FPG),2 hours postprandial glucose(2hPG),glycosylated hemoglobin Alc(HbAlc),fasting insulin(FINS),insulin resistance index(IRI)and insulin sensitivity index(ISI) were compared before and after treatment.ResultsAfter the transient intensive insulin therapy,UA,FPG,2hPG,HbAlc and IRI were significantly decreased(all P＜0.01);ISI was significantly increased(P＜0.01).ConclusionThe transient intensive insulin therapy can effectively mitigate insulin resistance and decreases the level of serum uric acid in newly diagnosed type 2 diabetic patients.

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