ObjectiveTo explore the effect of thyroid function on bone metabolism.MethodsSerum concentrations of FT3,FT4,PINP,BGP,ICTP,B-ALP are measured by radioimmunoassay(RIA)in 56 hyperthyroid patients and 56 healthy controls.ResultsThe levels of FT3,FT4,PINP,BGP,ICTP,B-ALP in hyperthyroid patients significantly higher than those of the healthy controls(P＜0.01),and the levels of FT3,FT4 were positively correlated to PINP,BGP,ICTP,B-ALP respectively(P＜0.01).ConclusionThyroid hormone might speed up bone turn over directly with increased bone resorption to induce bone mass loss in patients with hyperthyroid.

• ref