ObjectiveTo investigate the effect of the high-protein diet-based intensive nutritional support mode on nutritional indicators and immune function in patients with advanced non-small cell lung carcinoma and malignant hydrothorax. MethodsA total of 85 patients with advanced non-small cell lung carcinoma and malignant hydrothorax were selected as research objects and randomly divided into a control group (n=42) or an observation group (n=43). The control group was given standard dietary intervention, the observation group was given high-protein diet-based intensive nutritional support mode intervention, and both groups were intervened for 1 month. The nutritional indicators, immune function, and the incidence of complications were compared between the two groups. ResultsAfter 1 month of intervention, the serum prealbumin, hemoglobin, albumin levels; body mass index; serum CD3+, CD4+ levels; and CD4+/CD8+in the observation group were higher than those in the control group (all P＜0.05). During the intervention, there was no statistically significant difference in the incidence of pleural reaction or pneumothorax between the two groups (all P＞0.05), and the incidence of malnutrition in the observation group was lower than that in the control group (P＜0.05). ConclusionThe high-protein diet-based intensive nutritional support mode has a definite effect on patients with advanced non-small cell lung carcinoma and malignant hydrothorax, which can effectively improve patients′ nutritional indicators, enhance their immune function, and reduce the incidence of malnutrition.

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