ObjectiveTo explore the establishment of the intervention model on prevention of HIV high-risk behaviors to men who have sex with men(MSM).MethodsThrough “The family peer education” model to participate in peer education group,AIDS prevention and high-risk behavior intervention were carried out among 300 MSM through the investigation before and after the intervention,the AIDS knowledge,attitudes and behaviors and evaluated the effect of the intervention model.ResultsAfter the intervention,the AIDS prevention knowledge and risk behaviors of 300 MSM had been enhanged significantly.ConclusionThe “family peer education” model can effectively improve the MSM in AIDS prevention knowledge and corresponding changes the high-risk behavior,at the same time,we should focus our work of MSM on insisting on using condoms.