ObjectiveTo investigate the clinical efficacy of antibacterial agents combined with acupuncture in treatment of acute exacerbation of chronic obstructive pulmonary disease. MethodsA total of 60 cases of acute exacerbation of chronic obstructive pulmonary disease were selected and randomly divided into control group and study group,with 30 cases in each group. The control group was treated with cefoperazone-sulbactam sodium on the basis of conventional treatment while the study group was given acupuncture on basis of the control group, clinical effect, average days of hospitalization, drug utilization index (DUI), antibacterial use density,the rate of 30 days readmission, the total hospitalization expenditures and cost of the drugs between the two groups were compared. ResultsThe rate of clinical effect in the study group was 96.7% and the control group was 90.0%, there was no significant difference between the two groups(P＞0.05),but rank sum test show that the efficacy of the study group was significantly superior to the control group(P＜0.05); the average days of hospitalization, DUI, antibacterial use density, total hospitalization expenditures and cost of the drugs in the study group were significantly lower than those in the control group (P＜0.05); there were no untoward reactions in both study group and control group in the clinical trial. ConclusionsAcupuncture combined with antibacterial agents has definite clinical effect in treating acute exacerbation of COPD, which can effectively reduce the use of antibiotic, shorten the hospitalization time, decrease expenditure, and worthy of popularization and application.

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