ObjectiveTo investigate the efficacy and pregnancy outcome of insulin aspart injection combined with Astragalus sijunzi soup in patients with gestational diabetes mellitus. MethodsA total of 220 patients with gestational diabetes mellitus were randomly divided into observation group and control group, with 110 cases in each group. The control group were given insulin aspart injection, while the observation group were given Astragalus sijunzi soup on the basis of the control group.The clinical efficacy, time of reaching target of glucose, dosage of insulin, incidence of adverse reactions, perinatal conditions and pregnancy outcome between the two groups were compared. ResultsThe total effective rate was 83.6% in observation group and 70.1% in control group with significant difference (P＜0.05). Time of reaching target of glucose in observation group was significantly shorter than that in control group, and dosage of insulin in observation was significantly less than that in control group (P＜0.05) , the incidence rate of nausea, diarrhoea, hypoglycemia, hypertension during pregnancy, neonatal hypoglycemia, polyhydramnios in observation group were lower than those in control group (P＜0.05); the rate of abortion and preterm and the incidence of puerperal infection in the observation group were significantly lower than those in the control group (P＜0.05). ConclusionsInsulin aspart injection combined with Astragalus sijunzi soup has a significant curative effect on gestational diabetes, good for controlling of blood sugar level, and can reduce dosage of insulin and the incidence of adverse reactions, improve pregnancy outcome and worthy of popularization.

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