ObjectiveTo investigate the diagnostic value of quantitative scores of BI-RADS classification under tissue harmonic imaging combined with the ultrasound elasticity imaging in the benign and malignant breast lesions. MethodsTen sonographic features of 363 breast lesions confirmed by pathology were analyzed using tissue harmonic imaging, the points of sonographic features were assigned, and the integrated grading and classification of ultrasonic BI-RADS were performed, and then scoring for elasticity imaging was conducted on the basis of Bao-ming Luo improved 5-scoring system, finally, the diagnostic accuracy of BI-RADS grading, elasticity imaging and the combination of the two in diagnosing benign and malignant breast lesions were evaluated by comparing with pathologic results. Results(1)With pathological diagnosis as the gold standard, breast lesions composite score was identified as the 15 points, the grade of 4b was used as the cut-point of BI-RADS to diagnose the benign and malignant breast lesions, its sensitivity, specificity, positive predictive value, negative predictive value, diagnostic accuracy, Youden index were 80.3%, 95.4%, 89.9%, 90.6%, 90.3%, 0.76, respectively. (2) The score of elasticity imaging ≤3 was benign, while the score of elasticity imaging≥4 was malignant, its sensitivity, specificity, positive predictive value, negative predictive value, diagnostic accuracy, Youden index were 77.0%, 91.7%, 82.5%, 88.8%, 86.8%, 0.69, respectively.The diagnostic accuracy of combined diagnosis was higher than that of single diagnosis. ConclusionsUltrasound diagnostic indicator composite score for quantification of breast lesions based on BI-RADS classification diagnostics can objectify and normalize the ultrasonic report, and combined diagnosis can provide a more reliable basis for the evaluation of malignant potential of breast lesion.

• ref