内科

目的探讨急性脑出血伴系统性炎症反应综合征（SIRS）患者的病情及预后。方法将163例急性脑出血患者按有无伴发SIRS分为SIRS组75例和非SIRS组88例，均于入院当天、第3天分别进行头颅CT检查、GCS评分和神经功能缺损评分（NIHSS），比较两组患者相关资料。结果163例急性脑出血并发SIRS75例，发生率为46.01%。SIRS组GCS评分低、出血破入脑室发生率高（P＜0.05），SIRS组入院第3天脑出血量及NIHSS评分较入院时明显增加（P＜0.05），多器官功能障碍综合征（MODS）发生率为33.33%，病死率为30.67%，均高于非SIRS组的9.09%和6.82%（P均=0.000）。结论SIRS从多方面影响急性脑出血患者的病情，可作为急性脑出血病情进展的警示信号和预后判定指标。

ObjectiveTo explore the conditions and prognosis of patients with acute cerebral hemorrhage combined with systematic inflammatory response syndrome(SIRS).Methods163 patients with acute cerebral hemorrhage were divided into two groups based on combination of SIRS:SIRS group(n=75),non-SIRS group(n=88).The data included skull CT、Glasgow Coma Scale(GCS) scores、National Institute of Health stroke scale(NIHSS) scores were detected and compared at the first and third day of hospitalization.ResultsThe incidence of SIRS in acute cerebral hemorrhage was 46.01%(75 cases in 163patients).The GCS scores of SIRS group were lower and incidence of hemorrhage breaking into brain ventricles was higher compared with non-SIRS group.Hemorrhage volume and NIHSS scores of SIRS group were markedly increased 3 days after hospitalization(P＜0.05).The incidence of MODS in SIRS group was 33.33%,fatality rate 30.67%,higher than non-SIRS group′s 9.09% and 6.82%(P=0.000,respectively).The results showed that obviously increased as compared with non-SIRS group(P=0.000).ConclusionSIRS may influence the conditions of patients with acute cerebral hemorrhage in many ways.It may act as an important prognosis index and warning signal of acute cerebral hemorrhage prognosis.

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