ObjectiveTo investigate the effects of DAVID spine biomechanics training system-based rehabilitation training on the spine core musculature mechanical function and core muscle endurance in patients with ankylosing spondylitis (AS). MethodsThe clinical data of 115 patients with AS were retrospectively analyzed, and they were divided into a conventional group (57 cases) or a system group (58 cases) according to the rehabilitation pattern. The conventional group underwent exercise rehabilitation training, the system group underwent DAVID spine biomechanics training system-based rehabilitation training, and both groups were intervened continuously for 3 months. The spine core musculature mechanical function, core muscle endurance, and inflammatory indicators were compared between the two groups. ResultsAt the end of the 3-month intervention, the left rotation, right rotation, forward flexion, back extension, and abdominal and back muscle endurance levels in the two groups were higher than those before the intervention, and those in the system group were higher than those in the conventional group (all P<0.05). At the end of the 3-month intervention, CRP, TNF-α, and erythrocyte sedimentation levels in the two groups were lower than those before the intervention, and those in the system group were lower than those in the conventional group (all P<0.05). ConclusionsDAVID spine biomechanics training system-based rehabilitation training can improve the spine core musculature mechanical function and core muscle endurance and reduce the levels of inflammatory indicators in patients with AS.