Objective To investigate the anxiety symptoms and depressive symptoms, as well as self-awareness and its influencing factors, in children with somatic symptom disorder (SSD) in the joint consultation of Departments of Pediatrics and Psychiatry in a general hospital. Methods A total of 83 children with SSD were selected as the study subjects and divided into a neurological symptom group (n=44) or a digestive symptom group (n=39) according to their symptoms. Anxiety symptoms, depressive symptoms, and self-awareness were compared between the two groups, and the multivariate logistic regression model was used to analyze influencing factors of self-awareness in children with SSD. Results The total score of The Screen for Child Anxiety Related Emotional Disorders and the scores of its social phobia and school anxiety subscales of the neurological symptom group were higher than those of the digestive symptom group, and the freedom from anxiety subscore of Piers‑Harris Children's Self‑Concept Scale of the digestive symptom group was higher than that of the neurological symptom group (all P<0.05). The results of multivariate logistic regression model analysis showed that interpersonal relationships, being the only child, anxiety symptoms, and depressive symptoms were influencing factors of self-awareness in children with SSD (all P<0.05). Conclusion The anxiety symptoms and the self-awareness level differ between children with SSD with different symptoms in the joint consultation of Departments of Pediatrics and Psychiatry in a general hospital, and the self-awareness of children with SSD is related to interpersonal relationships, whether they are the only child, anxiety symptoms, and depressive symptoms. Therefore, in the treatment of children with SSD, more attention should be paid to their emotional state and improving their self-consciousness.