【Abstract】 Objective To analyze the 2022 health examination results of adults in Liaoning Electric Power Central Hospital and explore the distributive characteristics and rules of abnormal health examination results of adults, so as to provide a basis for the prevention and control of common diseases. Methods A total of 59,593 adults receiveing examinations in the Health Management Center of Liaoning Electric Power Central Hospital in 2022 were enrolled as research subjects, whose general data were analyzed, as well as results of the examinations, including electrocardiogram, chest/lung CT, color ultrasound for thyroid, breast, abdomen, and uterine adnexa, thin-prep cytology test (TCT), and bone mineral density test (ultrasound). Results Among the included physical examination items, the disease diagnosis or positive result whose detection rate ranked in the top 5 included thyroid nodules and/or cysts (58.52%), fatty liver (54.11%), pulmonary nodules (52.51%), abnormal electrocardiogram (32.60%), and decreased bone mineral density (31.21%). In males, the results were fatty liver (62.41%), thyroid nodules and/or cysts (55.44%), pulmonary nodules (51.17%), abnormal electrocardiogram (32.90%), and prostate enlargement (32.69%). In females, the results were thyroid nodules and/or cysts (65.17%), pulmonary nodules (55.55%), breast nodules and/or cysts (41.65%), uterine fibroids (36.66%), and fatty liver (35.80%). Except for the abnormal cytological changes in the TCT, all health examination items included in the research had statistically sighificant differences in the detection rates among groups with various ages (all P<0.001). Conclusion In Liaoning Electric Power Central Hospital, the 2022 abnormal health examination results of adults with different genders and ages have their specific distributive characteristics, and the detection rates of thyroid nodules and/or cysts, fatty liver, pulmonary nodules, abnormal electrocardiograms, and decreased bone mineral density are high, according to which the corresponding health examination plans should be formulated and targeted health education should be carried out.