目的观察心脏再同步起搏(CRT)治疗慢性充血性心力衰竭(CHF)的临床疗效。方法选择心功能Ⅲ~Ⅳ级(NYHA分级)的患者12例,治疗前行心脏彩色多普勒检查及心电图检查,符合美国、中国心脏CRT指南的适应证,行CRT起搏器植入,术后第1周及第4周返院复查心脏彩色多普勒检查及心电图检查,观察CRT起搏器植入术前后患者心功能及病情变化。结果CRT起搏器植入术治疗后12例患者心功能均明显改善,左室射血分数及左室充盈均增加,二尖瓣返流减少,NYHA心功能分级从Ⅲ~Ⅳ级提高到Ⅰ~Ⅱ级。结论心脏再同步起搏治疗慢性充血性心力衰竭近期疗效明显。
ObjectiveTo observe the clinical efficacy of cardiac resynchronization therapy (CRT) in patients with chronic congestive heart failure (CHF).Methods12 patients with a heart function ranging from III to IV grade (NYHA grading) were selected.All the patients were diagnosed by Doppler imaging and ECG check.CRT pacemakers were planted in patient’s heart after we found that they all had the indications to CRT.The patients were required to come back to make Doppler imaging and ECG check 1 week and 4 weeks after CRT,then their heart function and state of an illness were compared.ResultsAfter CRT,all the patients′ heart function were improved obviously.Both LVEF and LVEDD were increased,while secondary mitral regurgitation reduced,and NYHA functional class enhanced to I-II class.ConclusionCRT has a significant therapeutic effect in patients with CHF.