Objective To investigate the current status of comorbidity of chronic diseases in the population undergoing stroke risk screening in Dapeng New District, Shenzhen, and to analyze the characteristics of comorbidity of chronic diseases in this population, so as to provide a reference for the prevention and treatment of stroke in the community. Methods A total of 321 residents who established health records and underwent stroke risk screening at Kuichong and Sanxi Gaoyuan Community Health Service Centers in Dapeng New District were selected as the research subjects, their general characteristics, chronic diseases, and comorbidity of chronic diseases were collected, and the correlations between chronic diseases were analyzed. Results Among the 321 residents who underwent stroke risk screening in Dapeng New District, Shenzhen, 44 (13.7%) had a lower risk, 39 (12.1%) had a moderate risk, and 238 (74.1%) had a higher risk for stroke; the prevalence rate of hyperhomocysteinemia was higher in men than in women; the prevalence rate of diabetes mellitus was lower in people aged <60 years than in people aged ≥ 60 years, and the prevalence rates of dyslipidemia and obesity were higher in people aged <60 years than in people aged ≥ 60 years; the prevalence rate of comorbidity of chronic diseases was 74.45%, the prevalence rate of comorbidity of chronic diseases was higher in men than in women, and the prevalence rate of comorbidity of chronic diseases was higher in people with abdominal obesity than in people without abdominal obesity (all P<0.05). The contingency table's chi-square test results showed that hypertension was correlated with dyslipidemia (P<0.01). Conclusion The prevalence rate of comorbidity of chronic diseases is high among the population undergoing stroke risk screening, and it is recommended to apply the multi-disease co-management model to improve the management effect of chronic diseases and intervene for modifiable risk factors to reduce the incidence of stroke.

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