Objective To investigate the effects of Shensong Yangxin Capsules combined with atorvastatin on blood lipids and atherosclerosis in patients with coronary heart disease. Methods A total of 72 patients with coronary heart disease were selected as research subjects and randomly divided into a control group or a study group, with 36 cases in each group. The control group was treated with oral atorvastatin calcium tablets, on the basis of which the study group was treated with Shensong Yangxin Capsules, and both groups were treated for 6 months. The blood lipids levels, carotid artery intima-media thickness (IMT), and pulse wave velocity (PWV) before treatment and after 6 months of treatment, as well as the occurrence of adverse cardiovascular events during treatment, were compared between the two groups. Results After 6 months of treatment, the low-density lipoprotein cholesterol (LDL-C) level in the control group was lower as compared with that before treatment, the total cholesterol, triglycerides, and LDL-C levels in the study group were also lower as compared with those before treatment and those in the control group; the carotid artery IMT and PWV in the study group were lower than those in the control group (all P<0.05). During the treatment, there was no adverse cardiovascular event in the two groups. Conclusion In the treatment of patients with coronary heart disease, Shensong Yangxin Capsules can improve the blood lipid metabolism, effectively regulate blood lipids, alleviate their atheroscleroses, and reduce the risks of acute cardiovascular events.

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