【Abstract】 Objective To compare the effects of using intra-aortic balloon pump (IABP) at different times after surgery in patients with severe heart disease. Methods A retrospective analysis was performed on the clinical data of 82 patients undergoing IABP after surgery for severe heart disease. According to the timing of using IABP, the patients were divided into the early group (IABP applied within 6 hours after surgery, n=42) or the late group (IABP applied over 6 hours after surgery, n=40). The hemodynamic indexes, related clinical indicators, serological indexes, and incidence of complications were compared between the two groups. Results After 48 hours of using IABP, the mean arterial pressure and left ventricular ejection fraction of the two groups were higher than those before using IABP, and those of the early group were higher than those of the late group (all P<0.05). The indwelling time of IABP, the duration of mechanical ventilation, and monitoring time in the cardiac care unit in the early group were shorter than those in the late group (all P<0.05). After 48 hours of using IABP, the serum level of N-terminal pro-brain natriuretic peptide in the early group was lower than that in the late group, and the serum lactate clearance rate was higher than that in the late group (all P<0.05). The overall incidence of complications in the early group was lower than that in the late group (P<0.05). Conclusion Early IABP can promote the improvement of hemodynamic and serological indexes, shorten the clinical treatment time, and reduce the risk of complications in patients undergoing surgery for severe heart disease.

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