目的评价西药联合雾化吸入布地奈德治疗新生儿肺炎的疗效。方法将116例新生儿肺炎患儿采用随机数字表法分为观察组与对照组,对照组给予西医常规治疗,观察组在同对照组治疗基础上联合雾化吸入布地奈德治疗,比较患儿治疗效果。结果两组患儿的疗效比较差异有统计学意义(P<0.05),观察组治疗总有效率为94.83%,高于对照组的82.76%,两组比较差异具有统计学意义(P<0.05);治疗后,观察组患儿的平均二氧化碳分压为(38.45±2.03)mmHg,低于对照组的(44.61±3.11)mmHg;观察组患儿的平均氧合指数为(277.36±19.76)mmHg,高于对照组的(231.16±14.60)mmHg,两组比较差异均有统计学意义。观察组患儿的呼吸困难消失时间、肺部啰音消失时间和住院天数分别为(3.11±1.02)d、(5.28±1.14)d、(10.98±2.42)d,均较对照组短,两组比较差异具有统计学意义。结论采用雾化吸入布地奈德治疗新生儿肺炎的效果较好,提高了新生儿肺炎治疗总有效率,改善了患儿的动脉血气指标,提高了血氧饱和度,缓解了患儿呼吸困难症状,减少了患儿的住院天数,其疗效肯定,值得在临床上推广应用。
ObjectiveTo evaluate the effect of western medicine combined with nebulized budesonide in the treatment of neonatal pneumonia. Methods116 cases of neonatal pneumonia were divided into observation group and control group in accordance with the random number table. Cases in Control group were treated with western medicine while the cases in observation group were treated with nebulized budesonide on the based of control group. The treatment effect of each group was recorded. ResultsThe curative effect of two groups was significantly different (P<0.05). The total effective rate of observation group was 94.83%, significantly higher than that of control group which was 82.76%(P<0.05); after treatment, the average CO2 partial pressure of observation group was (38.45±2.03)mmHg, significantly lower than that of control group(231.16±14.60)mmHg,(P<0.05). The average oxygenation index of observation group was (277.36±19.76)mmHg, significantly higher than of control group(231.16±14.60)mmHg,(P<0.05). The time of breathing difficulties disappearing,pulmonary rales disappearing and the days of hospitalization in observation group were(3.11±1.02)days, (5.28±1.14)days and (10.98±2.42)days,respectively,were all shorter than those in control group,the difference were statistically significant (P<0.05). ConclusionsNebulized budesonide in the treatment of neonatal aspiration pneumonia has better clinical results, which can improve the total effective rate and arterial blood gas index, increase oxygen saturation, relieve breathing difficulties, and reduce the days of hospitalization, the curative effect is remarkable and worth widely used in clinical.