内科

目的分析冠心病发病的危险因素，为有效防治提供参考依据。方法选取行冠状动脉造影检查的患者100例为研究对象，将经冠状动脉造影确诊的冠心病患者50例作为研究组，将其余50例非冠心病患者作为对照组，比较两组患者在吸烟、家族史、高血压、糖尿病、高脂血症、BMI、性别、年龄、TC、TG、HDL-C及LDL-C方面的差异，同时进行多因素Logistic回归分析。结果两组患者在吸烟、家族史、高血压、糖尿病、高脂血症、BMI方面比较，差异具统计学意义（P＜0.05），两组的性别构成比、年龄、TC、TG、HDL-C及LDL-C水平方面比较，差异无统计学意义（P＞0.05）。Logistic 多元回归结果显示吸烟（OR=3.342）、高血压（OR=2.578）、糖尿病（OR=2.341）、高脂血症（OR=3.176）是冠心病发病的独立危险因素。结论吸烟、高血压、糖尿病、高脂血症为冠心病发病的独立危险因素，针对上述危险因素进行有效干预，可能有助于降低冠心病患病率。

ObjectiveTo study the risk factors of coronary heart disease, provide the evidences for the prevention of coronary heart disease. MethodsA total of 100 patients who underwent coronary angiography were selected and divided into study group ( patients with coronary heart disease) and control group (patients without coronary heart disease) according to the result of coronary angiography, with 50 cases in each group, the histories of smoking, diabetes and hypertension, hyperlipidemia, family history, BMI, sex ,age, TG, TC,HDL-C and LDL-C between two groups were compared. ResultsNo significant difference was found between two group in sex, age, TG, TC,HDL-C and LDL-C (P＞0.05), but the difference of histories of smoking, diabetes, hyperlipidemia and hypertension, family history, BMI between two group was significant (P＞0.05). Logistic showed that smoking (OR=3.342), hypertension (OR=2.578), diabetes mellitus (OR=2.341), hyperlipidemia (OR=3.176) were the independent risk factors of coronary heart disease. ConclusionsSmoking, hypertension, diabetes and hyperlipidemia were the independent risk factors of coronary heart disease, effective prevention should be take, which will decrease the occurrences of coronary heart disease.