ObjectiveTo discuss and study the application value of 12 leads ambulatory electrocardiogram and 64 slice spiral CT in the diagnosis of coronary artery disease. MethodsA total of 90 patients with suspected coronary heart disease admitted to our hospital from January 2012 to August 2015 were selected, all patients were performed coronary angiography, 12 lead dynamic electrocardiogram, 64 slice spiral CT, respectively.The results of coronary angiography was taken as golden criterion, the value of 12 leads ambulatory electrocardiogram, 64 slice spiral CT, and the combined examination of the two methods in the diagnosis of coronary artery disease were compared and analyzed. ResultsThe sensitivity, specificity, accuracy, positive predictive value and negative predictive value of 12 lead dynamic electrocardiogram in diagnosing coronary artery disease were 76.92%, 78.95%, 77.78%, 83.33% and 71.43%,respectively, and the single vessel disease detection rate of 12 lead dynamic electrocardiogram (56.52%) was significantly lower than the multiple lesions detection rate (93.10%, P＜0.05), the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of 64 slice spiral CT were 86.54%,31.58%、63.33%、63.38% and 63.16%, respectively, the combined examination of the two methods were 94.23%,84.21%、90.00%、89.09% and 91.43%, respectively.The sensitivity, specificity and positive predictive value of the combined examination of the two methods were significantly higher than those of 12 lead dynamic electrocardiogram and 64 slice spiral CT(P＜0.05). ConclusionsBoth 12 leads ambulatory electrocardiogram and 64 slice spiral CT have applied value in the diagnosis of coronary artery disease, combined the two can significantly enhance the sensitivity and specificity, and decrease the rate of misdiagnosis and missed diagnosis.

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