ObjectiveTo investigate the relationship between plasma apolipoprotein ratios (apoAl/apoB), BMI and degree of coronary artery stenosis. MethodsA total of 1079 patients who would accept coronary angiography were enrolled, the results of coronary angiography was evaluated by Gensini score, all patients were divided into coronary heart disease(CHD) group (940 cases,Gensini score＞0) and control group(139 cases,Gensini score=0)according to coronary artery angiography, and the coronary heart disease group was divided into mild lesion group(342 cases,1≤Gensini score＜30),moderate lesion group(345 cases, 30≤Gensini score＜60),severe lesion group(253 cases,Gensini score≥60)according to Gensini score.Height and weight of all patients were measured, and the level of blood lipid was detected, and body mass index (BMI), apoAl/apoB were calculated. ResultsCHD group was significantly older than control group (P＜0.05), and percentages of participants with hypertension, diabetes, smoking and family history of CHD in coronary heart disease group were significantly higher than those in control group (P＜0.05); BMI, the levels of TC, TG, LDL, apoB, Lp (a), HCY CHD in coronary heart disease group were significantly higher than those in control group (P＜0.05), and apoAl, apoAl/apoB, the levels of HDLwere significantly lower than those in control group (P＜0.05). Gensini score had positive correlations with age, history of hypertension, diabetes, smoking history, family history of coronary heart disease, BMI, TC, TG, LDL, apoB, LP (a), and HCY(P＜0.05), but had negative correlations with HDL、apoAl and apoAl/apoB(P＜0.05). History of hypertension, diabetes, family history of coronary heart disease, high BMI, high LDL, apoB, high Lp (a) were the independent risk factors for CHD, and apoAl and apoAl/apoB were protect factors. ConclusionsLow apoAl/apoB or high BMI are the risk factors for CHD, which can reflect the severity of coronary artery stenosis, predict the risk of CHD.

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