内科

目的探讨醒脑开窍针法联合依达拉奉、纤溶酶治疗脑梗死急性期患者的疗效及对神经功能的影响。方法将脑梗死急性期患者66例随机分为对照组和观察组，每组33例。对照组患者给予依达拉奉和纤溶酶治疗，观察组患者在依达拉奉和纤溶酶治疗的基础上加用醒脑开窍针治疗。治疗14 d后比较两组患者神经功能缺损评分（NIHSS）、日常生活能力Barthel指数（BI）评分、牛津残障评分（OHS）及临床疗效；治疗1 d、3 d、7 d、14 d后分别检测比较两组患者血清C-反应蛋白水平（CRP）；观察比较两组患者不良反应发生情况。结果治疗14 d后两组患者NIHSS、OHS评分均显著降低、BI评分显著升高（P＜0.01），观察组患者NIHSS、OHS评分显著低于对照组、BI评分显著高于对照组（P＜0.01）。观察组患者治疗总有效率（96.97%）显著高于对照组（75.76%），差异有统计学意义（P＜0.05）；观察组患者临床疗效优于对照组（P＜0.01）。治疗后3 d、7 d、14 d时，观察组CRP水平显著低于对照组，差异有统计学意义（P＜0.05或0.01）。治疗期间两组患者均未出现明显的不良反应。结论醒脑开窍针法联合依达拉奉、纤溶酶治疗，能够有效改善脑梗死急性期患者神经功能，临床疗效显著，不良反应少，值得推广使用。

ObjectiveTo investigate the influence of resuscitating acupuncture therapy combined with edaravone and fibrinolytic enzyme on nerve function in patients with acute cerebral infarction. MethodsSixty-six cases of patients with acute cerebral infarction were randomly divided into control group and observation group, with 33 cases in each group. The control group was treated with edaravone and fibrinolytic enzyme, while the observation group was treated with resuscitating acupuncture therapy on the basis of edaravone and fibrinolytic enzyme.The neurological deficit scores (NIHSS), Barthel index (BI), Oxford disability scores (OHS) and clinical efficacy were compared between the two groups after 14 days of treatment.The levels of C-reaction protein (CRP) in both groups were detected after 1 day,3 days,7 days and 14 days of treatment, and the incidence rates in the two groups were analyzed. ResultsAfter 14 days of treatment, the scores of NIHSS and OHS decreased significantly in the two groups in contrast with those before treatment, and the decrease of the indexes mentioned above was more significant in the observation group (P＜0.01); BI scores in the two groups were significantly higher than those before treatment (P＜0.01), and the decrease was more significant in the observation group (P＜0.01). The total effective rate of treatment in the observation group (96.97%) was significantly higher than that in the control group (75.76%, P＜0.05), and the clinical efficacy in the observation group was significantly superior to that in the control group (P＜0.01). After 7 days, 14 days of treatment, the CRP level in the observation group was lower than that in the control group (P＜0.05 or P＜0.01). No obvious adverse reactions was found in two groups during the treatment. ConclusionsResuscitating acupuncture therapy combined with edaravone and fibrinolytic enzyme can effectively improve the nerve function in patients with acute cerebral infarction, with significant effect and less adverse reactions, which is worthy of promotion and application in clinical.