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城市空气污染与儿童哮喘发病流行病学调查分析
Epidemiological study on the relationship between air pollution and the incidence rate of asthma in children

内科 201604期 页码:536-539

作者机构:甘肃省妇幼保健院,兰州市730050

基金信息:*通讯作者

DOI:DOI:10.16121/j.cnki.cn45-1347/r.2016.04.09

  • 中文简介
  • 英文简介
  • 参考文献
目的探讨城市空气污染与儿童哮喘发病的关系。方法对某城市不同空气污染分区长期居住的1 200名儿童进行检查,其中重度污染区、中度污染区和轻度污染区居住儿童各400名,对哮喘患儿流行病学特征进行统计分析,并分别采用单因素方差和多因素Logistic回归分析方法分析影响儿童发生哮喘的空气污染相关危险因素。结果本次共调查1 200名儿童,发现哮喘患儿94例,哮喘检出率为7.83%,男性高于女性,年龄<5岁、空气污染区居住时间≥5年儿童检出率较高,慢性持续期哮喘患儿所占比较较高。患儿以喘咳、胸闷、呼吸困难、气促、双肺可闻及弥漫性哮鸣音等为主要临床表现。被动吸烟、家属抽烟、家养皮毛动物、不安装排油烟机、室内通风状况差、不带口罩防护、有近距离污染源、居住在重度空气污染区的儿童,哮喘发病检出率较高,与相反情况儿童比较差异有统计学意义(P<0.05)。影响儿童哮喘发病、与空气污染相关的独立危险因素有重度空气污染、近距离污染源和被动吸烟,而安装排油烟机和口罩防护为保护性因素。结论 空气污染和儿童哮喘发病紧密关联,被动吸烟、近距离污染源和重度空气污染等均是儿童哮喘发病的独立危险因素,而安装排油烟机和口罩防护是其保护性因素。采取综合性防治措施才能有效降低儿童哮喘的发病率,促进儿童正常发育、健康成长。
ObjectiveTo discuss the relationship between air pollution and the incidence rate of asthma in children. MethodsA total of 1200 children permanently living in different air pollution regions in a city were enrolled, including 400 children from heavily polluted region, 400 children from moderately polluted region and 400 children from slightly polluted region.The epidemiological characteristics of children with asthma was statistically analyzed, and the risk factors of air pollution that lead to asthma in children was determined by single factor variance and multiple factor Logistic regression analysis. ResultsThere were 94 cases with asthma in the 1200 children, the incidence rate of asthma was 7.83%, male, age less than 5 years old, air pollution of residential area more than 5 years of time had a higher incidence rate, and asthma in chronic persistent accounts for more percentage. the main clinical symptoms of asthma were cough, dyspnea, chest tightness, shortness of breath,the lungs heard and diffuse wheezing. The children who living in adverse circumstances (such as passive smoking, family smoking, domestic fur animals, not to install fume hood, poor indoor ventilation condition, protection with out mask, near distance pollution source, heavily polluted region) had a significantly higher detection rate of asthma compare with those living in good circumstances (P<0.05). Severe air pollution, near pollution source and passive smoking were the independent risk factors of asthma in children, while the install fume hood and mask protection were the protective factors. ConclusionsSevere air pollution, near pollution source and passive smoking are the independent risk factors of asthma in children, and the install fume hood and mask protection are the protective factors. Some comprehensive measures must be taken to reduce the morbidity of asthma in children, and promote the normal development of children.

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