目的探讨生活方式干预联合降脂药治疗退休老年高脂血症患者的临床效果。方法将112例退休老年高脂血症患者随机分为干预组和常规组,每组56例。常规组患者给予降脂药治疗,干预组患者进行生活方式干预联合降脂药治疗,比较两组患者治疗前及治疗后6个月、12个月三酰甘油、总胆固醇水平的变化,以及患者合理运动、合理饮食及合理用药的依从性。结果治疗前两组患者三酰甘油、总胆固醇水平比较差异无统计学意义(P>0.05)。治疗后6个月、12个月后,干预组患者三酰甘油、总胆固醇水平均低于常规组,差异有统计学意义(P<0.05);干预组患者合理运动、合理饮食及合理用药依从性均高于常规组,差异有统计学意义(P<0.05)。结论生活方式干预联合降脂药治疗可有效改善退休老年高脂血症患者的不良生活习惯,更好地控制血脂水平。
ObjectiveTo explore the clinical effect of lifestyle intervention combined with lipid-lowering drugs in retired elderly patients with high cholesterol. MethodsA total of 112 retired elderly patients with high cholesterol were randomly divided into intervention group and conventional group, with 56 cases in each group. The conventional group treated with lipid-lowering drugs, while the intervention group received lifestyle intervention combined with lipid-lowering drugs, the levels of triglycerides, total cholesterol were compared between two groups after 6 and 12 months of treatment, and the patients’ compliance to proper exercise,reasonable diet and rational administration in the two groups was also observed. ResultsBefore treatment, that was no significant difference in the levels of triglycerides, total cholesterol between two groups (P>0.05), after 6 and 12 months of treatment, the levels of triglycerides, total cholesterol in the intervention group were significantly lower than those in the conventional group (P<0.05); the patients’ compliance to proper exercise, reasonable diet and rational administration in the intervention group was significantly higher than those in the conventional group (P<0.05). ConclusionsLifestyle intervention combined with lipid-lowering drug in treatment of retired elderly patients with high cholesterol can control the levels of lipid and change bad living habit.