【Abstract】ObjectiveTo observe the effect of Xue fu Zhu yu Decoction combined with Oxycodone Hydrochloride in the treatment of patients with blood stasis type of cancer pain. MethodsA total of 180 patients with blood stasis type of cancer pain were randomly divided into control group and observation group, 90 in each group. The control group was treated with Oxycodone Hydrochloride. The observation group were treated by Xuefu Zhuyu Decoction combined with Oxycodone Hydrochloride. The two groups were treated with 28 d. Effect of pain treatment, quality of life, time to onset of pain relief, duration of analgesia, daily dosage of Oxycodone Hydrochloride and adverse reactions were compared between the two groups after treatment. ResultsThe total effective rate of the observation group (90%) was higher than that of the control group (73.3%), and the observation group was better than that of the control group (P＜0.01). The two groups of patients with NRS scores were decreased, KPS scores were increased after treatment(P＜0.05). The NRS score of the observation group was lower than that of the control group, KPS score was higher than the control group (P＜0.05). The time to onset of pain relief in the observation group was shorter than that in the control group, and the duration of pain relief was longer than that in the control group (P＜0.01). The average daily dosage of Oxycodone Hydrochloridein of the observation group was less than the control group (P＜0.01). The incidence of adverse reactions in the observation group was lower than that in the control group (P＜0.05) . ConclusionThe treatments of Xuefu Zhuyu Decoction combined with Oxycodone Hydrochloride can significantly improve the patient′s pain and quality of life of blood stasis type of cancer pain, significantly reduce the average daily dosage of Oxycodone Hydrochloridein and adverse reactions of the patients.

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