ObjectiveTo investigate the relationship between glycated hemoglobin (HbA1c) levels in pregnant women with gestational diabetes mellitus（GDM） with blood glucose level in the newborns who delivery. Methods166 GDM pregnant women and their newborn babies were selected in our hospital for regular delivery and hospitalization. According to the HbA1c levels of pregnant women were divided into normal HbA1c group (HbA1c＜6%, 91 cases) and high HbA1c group (HbA1c≥6%, 75cases), and their babies were divided into normal HbA1c group babies and high HbA1c group babies. The blood glucose and insulin levels in 1h after birth and the incidence of hypoglycemia in the two groups babies were compared. The level of HbA1c in GDM pregnant women and the blood glucose level of 1h after birth were analyzed. ResultsThere were significant differences in the levels of BMI, fasting blood glucose and insulin in the two groups of GDM pregnant women (P＜0.05). The difference of blood glucose and insulin levels between the two groups of newborn babies after birth was statistically significant (P＜0.01). The incidence of hypoglycemiain of the normal HbA1c group babies was 4.39% in 1h after birth, the high HbA1c group babies was 17.33%. The difference between the two groups was statistically significant (P＜0.01). The HbA1c level of GDM pregnant women was negatively correlated with the level of blood glucose of the babies in 1h after birth (R=0.86, P＜0.01). ConclusionNewborns delivered by GDM pregnant women have hyperinsulinemia and high incidence of hypoglycemia. Scientific monitoring of the HbA1c level of pregnant women and the level of blood glucose in the newborns can accurately predict the incidence of hypoglycemia in neonates, so that we can intervene in a timely manner to minimize the damage of glucose metabolism disorder to newborns.

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