目的探讨温阳赞育汤治疗肾阳虚型男性不育症患者的临床疗效。方法选取2010年1月至2016年6月我院收治的肾阳虚型男性不育症患者203例为研究对象,采用随机数字表法分为观察组(101例)和对照组(102例)。观察组患者采用温阳赞育汤治疗,对照组患者采用五子衍宗丸治疗,疗程3个月。检测比较两组患者治疗前后的精子密度、精子成活率、(A+B)级精子所占比例以及精子畸形率。结果治疗前,两组患者的精子密度、精子成活率、(A+B)级精子所占比例、精子畸形率比较差异均具无统计学意义(P>0.05)。治疗3个月后,两组患者的精子密度、精子成活率、(A+B)级精子所占比例均显著升高,精子畸形率均显著降低(P<0.05);观察组患者的精子密度、精子成活率、(A+B)级精子所占比例明显高于对照组,精子畸形率显著低于对照组(P<0.05)。结论温阳赞育汤治疗肾阳虚型不育症患者疗效显著,临床治疗效果显著优于口服五子衍宗丸治疗。
ObjectiveTo investigate the curative effect of Wenyang Zanyu decoction in treating male infertility with kidney yang deficiency. Methods203 cases of kidney yang deficiency male infertility with kidney yang deficien treated in our hospital from January 2010 to June 2016 were selected. They were randomly divided into observation group (101 cases) and control group (102 cases). The observation group was treated with Wenyang Zanyu decoction. The control group was treated with Wuzi Yanzong pill. The two groups were treated for 3 months. The sperm density, the survival rate of sperm, the proportion of (A+B) grade spermatozoa and the rate of sperm malformation before and after treatment were compared between the two groups. ResultsBefore treatment, there was no significant difference in sperm density, sperm survival rate, (A+B) grade spermatozoa proportion and sperm malformation rate between the two groups (P>0.05). After 3 months of treatment, the sperm density, sperm survival rate and (A+B) grade spermatozoa proportion of the two groups increased significantly, and the rate of sperm deformity was significantly decreased (P<0.05). The sperm density, sperm survival rate and (A+B) grade spermatozoa proportion in the observation group were significantly higher than those in the control group, and the sperm deformity rate was significantly lower than that in the control group (P<0.05). ConclusionThe effect of Wenyang Zanyu decoction in treating male infertility with kidney yang deficiency is significant. The clinical curative effect was significantly better than Wuzi Yanzong pill.