ObjectiveTo observe the clinical efficacy of Sangeng Jiangqi decoction combined with acupuncture in the treatment of non erosive gastroesophageal reflux disease. Methods92 patients with non erosive gastroesophageal reflux disease were treated in our hospital from July 2016 to July 2017 were divided into the control group and the observation group, 46 cases in each group. The control group were treated with Sangeng Jiangqi decoction. The observation group were treated with Sangeng Jiangqi decoction combined with acupuncture. The two groups were treated for 12 weeks. The clinical efficacy of two groups were compared. Serum gastrointestinal hormone levels, vasoactive intestinal peptide levels and changes of 24h pH in the two groups after treatment were compared between the two groups. ResultsAfter 12 weeks of treatment, the clinical efficacy of the observation group was better than that of the control group. The total effective rate (95.65%) of the observation group was significantly higher than that of the control group (78.36%), the difference was statistically significant (P＜0.05). After treatment, the levels of motilin and gastrin in the observation group were significantly higher than those in the control group, and the vasoactive intestinal peptide level was significantly lower than that in the control group. The difference was statistically significant (P＜0.01). The pH value of the esophagus in the observation group was better than that in the control group within 24 hours(P＜0.01). ConclusionThe combination of Sangeng Jiangqi decoction and acupuncture in the treatment of patients with non erosive gastroesophageal reflux disease can improve the level of motilin and gastrin, reduce the secretion of vasoactive intestinal peptide, inhibit the secretion of gastric acid, improve the gastric motility, and improve the therapeutic effect. It is worth popularizing in clinical application.

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