ObjectiveTo analyze the risk factors of in-hospital death in patients with acute heart failure (ACHF) and to improve the level of clinical diagnosis and treatment. Methods408 patients with acute exacerbation of chronic heart failure admitted to our hospital from February 2015 to January 2017 were selected as subjects. The clinical data of the patients were collected and divided into survival group (358 cases) and death group (50 cases) according to the prognosis of the patients. Univariate analysis and multivariate logistic regression analysis were performed on the factors affecting the hospital mortality. ResultsUnivariate analysis showed that CHF course, comorbid disease, NYHA cardiac function grading, LVEF, BUN, blood sodium, pulmonary wet snoring/chest X-ray congestion/pulmonary edema/pleural effusion, lower extremity/ankle edema, congestive liver Swollen/ascites status compared with surviving patients. The differences were statistically significant (P＜0.05). Multivariate logistic regression analysis showed left ejection fraction ＜45%, BUN＞6.8 mmol/L, blood sodium＞146 or ＜135 mmol/L, pulmonary wetness/thoracic pulmonary congestion/pulmonary edema/thoracic cavity Fluid, congestive hepatomegaly/ascites is an independent risk factor for hospital mortality in patients with ACHF. ConclusionThe factors leading to hospital death in patients with ACHF are complicated. Left heart ejection fraction, BUN, and abnormal blood sodium levels are independent risk factors for hospital death. Patients with clinical ACHC should pay attention to their heart function, water and sodium retention and renal function. Patients with sodium and water retention must take effective measures in time to reduce the occurrence of death in hospital.

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