ObjectiveTo investigate the correlation of glycolipid metabolism, biochemical indexes, inflammatory markers and lactobacillus level in diabetic patients. MethodsA total of 120 cases of diabetes patients treated in our hospital during the period of March -2018 in June 2017 were selected as study group. At the same time,a total of 120 healthy subjects were selected as the control group at the period of health examination. Enzyme linked immunosorbent assay was used to observe the inflammatory indicators of the two groups,automatic life analyzer was used to detected the level of glycolipid metabolism,and the level of lactobacilli of two groups was measured by fluorescence quantitative polymerase chain reaction. ResultsThe the level of lactobacilli,peripheral blood fasting blood glucose (FBG), three acyl glycerol (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), glycosylated hemoglobin (HbAlc), lipoprotein binding protein (LBP), tumor necrosis factor (TNF-α), interleukin 1 beta (IL-1β),interleukin-6 beta (IL-6β) of study group was significantly higher than those in the control group,with statistical significance(P＜0.05),the content of soluble lipoprotein cholesterol (sCD14) and interleukin 10 beta (IL-10β) in the study group was significantly lower than those in the control group,with statistical significance(P＜0.05). ConclusionFor diabetic patients,the degree of inflammatory reaction were significantly higher than that of healthy people,the glycolipid metabolism level was lower than that of healthy controls,and the lactobacillus level in vivo was significantly higher than that of healthy people.The level of LDL-C was negatively correlated with the level of lactobacillus,and the level of TNF-α and IL-6β was positively correlated with the level of lactobacillus.

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