ObjectiveTo observe the effects of different treatments on testosterone and sperm in patients with kidney-yang deficiency male infertility. Methods203 cases of male infertility patients with kidney yang deficiency were treated in our hospital from September 2015 to June 2018, which were randomly divided into study group (100 cases) and control group (103 cases). The study group were treated with Wenyang Zanyu decoction, and the control group were treated with Wuzi Yanzong pill. The treatment was 1 month for 1 course and 3 courses for continuous treatment. Serum testosterone levels, sperm morphology, semen volume, and liquefaction time were compared between the two groups before and after treatment. ResultsAfter 3 months′ treatment, the total effective rate of the study group was 83.0%, and the control group was 66.0%; the difference between the two groups was statistically significant (P＜0.05). After treatment, the serum testosterone levels of the two groups were significantly increased. The normal morphology of sperm and semen increased significantly, and the sperm liquefaction time was significantly shortened. The serum testosterone level, normal spermatozoa rate and semen volume in the study group were significantly higher than those in the control group. The sperm liquefaction time was significantly shorter than that in the control group, and the difference was statistically significant (P＜0.05). ConclusionWenyang Zanyu Decoction can improve the serum testosterone level and semen quality more effectively than Wuzi Yanzong pill in patients with kidney yang deficiency infertility.

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