ObjectiveTo study the 2 year survival rate and prognostic factors after intensity-modulated radiotherapy for advanced nasopharyngeal carcinoma. Methods80 patients with advanced nasopharyngeal carcinoma treated in our hospital were selected. All cases were treated with intensity-modulated radiation therapy (IMRT). 4 weeks after radiotherapy, the effect of radiotherapy was evaluated; after 2 years of follow-up, the 2-year survival rate of the patients was analyzed, and the univariate and multivariate logistic regression analysis were performed to investigate the risk factors of prognosis. Results4 weeks after radiotherapy, the control rate of tumor was 88.75%. 2 years after radiotherapy, the progression free survival rate was 65.0%, the overall survival rate was 77.5%. The logistic multivariate analysis showed that the age, tumor T stage and N stage were risk factors for prognosis, the palliative surgery was a positive factor for prognosis. ConclusionThe IMRT radiotherapy for advanced nasopharyngeal carcinoma can achieve a high tumor control rate. The age, tumor T stage and N stage are important prognostic factors, and palliative surgery can improve prognosis of advanced nasopharyngeal carcinoma.

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