ObjectiveTo study the value of serum D-dimer level in evaluating the prognosis in patients with acute myocardial infarction (AMI). Methods120 patients with AMI who treated in two hospitals of Jiaozuo city from January 2014 to December 2015 were selected. The levels of serum D-dimer, cardiac troponin I (cTnI) and N-terminal pro-brain natriuretie peptide (NT-ProBNP) in patients were detected. According to the level of D-dimer, the patients were divided into low D-dimer level group (≤0.83 mg/L) and high D-dimer level group (＞0.83 mg/L). Kaplan-Meier survival curve was draw to compare the difference of prognosis between the two groups. Pearson regression was used to analyze the potential correlation between D-dimer and other two serum factors (cTnI and NT-ProBNP). Finally, ROC curve was draw to evaluate the value of serum D-dimer level in predicting the prognostic in patients with AMI. ResultsKaplan-Meier survival curve showed that the 1-year survival rate of patients in the high D-dimer level group was significantly lower than that in the low D-dimer group(P＜0.05). Pearson regression showed the positive correlation between D-dimer and cTnI, NT-ProBNP (r=0.748，P=0.000；r=0.612，P=0.000). The area under the ROC curve was 0.782, with the most appropriate cut-off value of D-dimer to predict the prognostic in patients with AMI was 1.223 mg/L (with sensitivity 65.40%, specificity 66.70%). ConclusionSerum D-dimer level was positively correlated with cTnI and NT-ProBNP levels in patients with AMI. Serum level of D-dimer had the potential value to predict the prognostic of patients with AMI.

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