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阿奇霉素联合妇康健合剂治疗支原体属感染性盆腔炎患者效果观察
Observation on the effect of azithromycin combined with Fukangjian agent on treatment of patients with mycoplasma-infective pelvic inflammatory disease

内科 201813卷05期 页码:760-762+693

作者机构:广东省惠州市惠东县人民医院,惠州市516300

基金信息:

DOI:DOI:10.16121/j.cnki.cn45-1347/r.2018.05.25

  • 中文简介
  • 英文简介
  • 参考文献
目的探讨阿奇霉素联合妇康健合剂治疗支原体属感染性盆腔炎患者的临床效果。方法选取2016年2月至2018年1月我院妇科收治的支原体属感染性盆腔炎患者174例为研究对象,随机分为观察组和对照组,每组87例。对照组患者给予阿奇霉素治疗,观察组患者在对照组治疗的基础上加服妇康健合剂治疗。检测比较治疗前后两组患者外周血T细胞亚群水平及子宫血流动力学状况;比较两组患者的临床疗效。结果观察组患者的治疗总有效率(94.25%)显著高于对照组(86.21%),差异具有统计学意义(P<0.05)。治疗4周后,两组患者外周血CD4+、CD4+/CD8+、RI、PI、Vmin水平均显著提高,而CD8+水平显著降低,观察组患者外周血CD4+、CD4+/CD8+、RI、PI、Vmin水平均显著高于对照组,CD8+水平显著低于对照组,差异均有统计学意义(P<0.05)。观察组患者的不良反应发生率(8.05%)与对照组(5.75%)比较,差异无统计学意义(P>0.05)。结论阿奇霉素联合妇康健合剂治疗支原体属感染性盆腔炎患者临床效果显著,能有效提高患者的免疫功能,改善患者子宫血流动力学状况,促进康复,具有良好的治疗安全性。
ObjectiveTo observe the clinical effect of azithromycin combined with Fukangjian agent in the treatment of patients with mycoplasma-infective pelvic inflammatory disease. MethodsA total of 174 patients with mycoplasma-infective pelvic inflammatory disease admitted to our hospital from February 2016 to January 2018 were selected as subjects and randomly divided into observation group and control group, with 87 cases in each group. Control group were treated with azithromycin, and observation group were treated with Fukangjian agent on the basis of therapeutic method of control group. The T lymphocyte subset levels and uterine hemodynamics indicators of the two groups were compared before and after treatment. The clinical curative effect of the two groups was compared. ResultsThe total effective rate of observation group (94.25%) was higher than that of the control group (86.21%), the difference was statistically significant (P<0.05). After 4 weeks of treatment, the levels of CD4+, CD4+/CD8+, RI, PI and Vmin in peripheral blood of the two groups were significantly increased, while the CD8+ level was significantly decreased; and the levels of CD4+, CD4+/CD8+, RI, PI and Vmin in peripheral blood of observation group were significantly higher than that of control group, while the CD8+ level was significantly lower than of control group, the difference were statistically significant (P<0.05). The incidence of adverse reactions of the observation group (8.05%), higher than 5.75% of the control group, but the difference was not statistically significant (P>0.05). ConclusionAzithromycin combined with Fukangjian agent is effective in the treatment of mycoplasma-infective pelvic inflammatory disease. It can promote immune functionand, improve uterine hemodynamics, facilitate rehabilitation and show high clinical safety.

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