ObjectiveTo explore the clinical effect of early enteral nutrition support combined with probiotics in the treatment of patients with septic shock. Methods66 patients with sepsis and shock admitted to our hospital from April 2015 to November 2017 were selected as subjects and randomly divided into observation group (32 cases) and control group (34 cases) according to the order of admission. The patients in the control group were given early enteral nutrition support treatment, and the patients in the observation group were treated with probiotics on the basis of the treatment of the control group. The clinical effects of the two groups of patients were compared. ResultsAfter 2 weeks of continuous treatment, serum total protein, hemoglobin, and serum albumin were significantly increased in both groups, the levels of these three indicators in the observation group were significantly higher than those in the control group (P＜0.05). The mechanical ventilation and ICU hospitalization time in the observation group were significantly shorter than those in the control group (P＜0.05). There was no significant difference in hospital mortality between the two groups (P＞0.05). ConclusionEarly enteral nutrition support combined with probiotics treatment can significantly improve the nutritional status of patients with septic shock, shorten the mechanical ventilation time and hospitalization time. It is of great significance to guide clinical treatment.

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