ObjectiveTo analyze the clinical value of serum N-terminal B-type natriuretic peptide(NT-proBNP) level applied to differential diagnosis and assessment on elderly patients with acute dyspnea. MethodsA total of 100 elderly patients with acute dyspnea admitted to our hospital from May 2016 to May 2018 were randomly selected as the research objects, including 50 cases with cardiogenic dyspnea (group) and 50 cases with pulmonary dyspnea (group). Serum NT-proBNP levels, left ventricular end-diastolic diameter (LVEDD) and left ventricular ejection fraction (LVEF) were compared between the two groups. Patients were graded by cardiac function and compared with different grades in serum NT-proBNP level, LVEDD and LVEF, and the relationship between serum NT-proBNP level and LVEF was analyzed. ResultsThe cardiogenic dyspnea group had significantly higher (bigger) serum NT-proBNP level and LVEDD as well as lower LVEF in comparison with the pulmonary dyspnea group (P＜0.05). Serum NT-proBNP level and LVEDD on patients with cardiogenic dyspnea in ascending order were grade Ⅱ, grade Ⅲ and grade Ⅳ, and LVEF were grade Ⅳ, grade Ⅲ and grade II, the difference was statistically significant (P＜0.05). The results of Pearson analysis showed that serum NT-proBNP level were negatively correlated with LVEF on patients with cardiogenic dyspnea (r=-0.685, P＜0.017). ConclusionSerum NT-proBNP level has a high clinical application value to differential diagnosis and assessment on elderly patients with acute dyspnea; it is helpful for the differential diagnosis of cardiogenic and pulmonary dyspnea; and it has great significance on taking corrective measures and saving patients′ lives in time.

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