ObjectiveTo observe the clinical efficacy of bronchoalveolar lavage combined with topical administration of etimicin on patients with bronchiectasis and infection. MethodsA total of 160 patients with bronchiectasis and infection admitted to our hospital from July 2016 to June 2018 were selected and randomly divided into the control group (75 cases) and the observation group (85 cases). On the basis of conventional symptomatic and anti-infective treatment, the control group was treated with bronchoalveolar lavage, while the observation group was treated with topical administration of etimicin on the basis of treatment in the control group. After 2 weeks of treatment, the efficacy, clinical manifestation, arterial oxygen partial pressure (PaO2), oxygen saturation (SaO2), arterial carbon dioxide partial pressure (PaCO2) and complications incidence rate were compared between the two groups. ResultsThe total effective rate of treatment in the observation group (95.3%) was significantly higher than that in the control group (84.0%), and the difference was statistically significant (P＜0.05). The time of fever subsidence, cough improvement and pulmonary inflammatory lesions disappearance in the observation group were significantly shorter than those in the control group, and the difference was statistically significant (P＜0.05). After 2 weeks of treatment, the PaO2, SaO2 and PaCO2 in both groups significantly improved; the improvement in the observation group was better than that in the control group, and the difference was statistically significant (P＜0.05). There was no statistically significant difference in complications incidence rate between the two groups during treatment (P＞0.05). ConclusionThe clinical efficacy of bronchoalveolar lavage combined with topical administration of etimicin on patients with bronchiectasis and infection is prominent. It can significantly improve clinical symptoms and blood gas status; it has high safety and it is worthy of promotion and application.

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