ObjectiveTo explore the effect of Shufeng Qingre decoction in patients with acute pharyngitis and the influence on the level of inflammatory factor. MethodsA total of 153 patients with acute pharyngitis admitted to our hospital from January to June 2019 were enrolled as the objects. They were divided into observation group (76 cases) and control group (77 cases) in accordance with random number table method. The control group were treated with Watermelon Frost Lozenges, whereas the observation group were treated with Shufeng Qingre decoction. After 1 month of treatment, the clinical therapeutic effects of the two groups were observed and compared. The tumor necrosis factor-α (TNF-α), interleukin-1 (IL-1), interleukin-2 (IL-2), and interleukin-6 (IL-6) levels between the two groups were detected and compared before and after treatment. The occurrence of adverse reactions between the two groups was observed and compared during the treatment. ResultsAfter 1 month of treatment, the total effective rate of treatment in the observation group (89.47%) was significantly higher than that in the control group (75.32%), with statistically significant difference (P＜0.05). The levels of TNF-α, IL-1 and IL-6 were significantly decreased in both groups, whereas IL-2 level was significantly increased. The levels of TNF-α, IL-1 and IL-6 in the observation group were significantly lower than those in the control group, while the level of IL-2 was significantly higher than that of the control group. The difference was statistically significant (P＜0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups during treatment (P＞0.05). ConclusionShufeng Qingre decoction has a significant clinical effect in the treatment of patients with acute pharyngitis. It can significantly reduce the level of inflammatory factor, and has a high clinical applicable value.

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