内科

目的探讨难治性肺炎支原体肺炎（MPP）患儿发病的危险因素。方法回顾性分析2018年4月至2019年4月广东省惠州市第三人民医院收治的172例MPP患儿的临床资料，对难治性MPP患儿（54例）和普通MPP患儿（118例）的性别、年龄、住院时间、发热时间、有无侵入性操作、居住环境、发病季节、病变位置、腹腔有无积液、是否存在反复呼吸道感染等情况进行比较分析，对难治性MPP患儿发病的危险因素进行多因素Logistic回归分析。结果单因素分析结果显示，难治性MPP患儿的年龄、住院时间、发热时间、反复呼吸道感染情况与普通MPP患儿比较差异有统计学意义（P＜0.05）。多因素Logistic回归分析结果显示，年龄≤2岁、住院时间＞11 d、发热时间＞15 d、反复呼吸道感染是难治性MPP患儿发病的独立危险因素。结论难治性MPP患儿发病的危险因素可能比较多，其中年龄≤2岁、住院时间＞11 d、发热时间＞15 d、反复呼吸道感染是难治性MPP患儿发病的独立危险因素，在该疾病的诊治中应给予高度关注。

ObjectiveTo explore the risk factors for incidence of children with refractory mycoplasma pneumonia (MPP). MethodsThe clinical data of 172 children infected with MPP admitted to our hospital from April 2018 to April 2019 were retrospectively analyzed. The gender, age, hospital stays, fever time, whether there was invasive operation, living environment, incidence season, lesion location, whether there was seroperitoneum, and whether there was repeated respiratory infection were compared and analyzed between 54 children with refractory MPP and 118 children with common MPP. A multivariate logistic regression analysis was conducted on the risk factors for children with refractory MPP. ResultsResults of univariate analysis revealed that the comparison in age, hospital stays, fever time, repeated respiratory infected condition between the children with refractory MPP and common MPP had statistically significant difference (P＜0.05). Results of multivariate logistic regression analysis revealed that age ≤ 2 years old, hospital stays ＞11 days, fever time ＞15 days, repeated respiratory infection were independent risk factors for the prevalence of children with refractory MPP. ConclusionThere are many risk factors for incidence of children with refractory MMP. Among them, age ≤ 2 years old, hospital stays ＞11 days, fever time ＞15 days, and repeated respiratory infection were independent risk factors for incidence of children with refractory MMP. Great concern should be given to the diagnosis and treatment of this disease.