目的探讨子宫内膜异位症并发不孕患者宫-腹腔镜联合治疗后不孕的危险因素,提高患者的术后妊娠率。方法选取2013年4月至2014年4月我院收治的子宫内膜异位症不孕患者98例为研究对象。通过查阅患者病历,随访患者3年,收集患者的相关资料。根据术后妊娠情况,将患者分为妊娠组(58例)和未妊娠组(40例)。通过比较两组患者的年龄、不孕年限、不孕类型、r-AFS分期、病理分型、使用GnRH以及促排卵治疗等情况,以及多因素Logistic回归分析,探讨子宫内膜异位症并发不孕患者宫-腹腔镜联合治疗后不孕的危险因素。结果单因素分析结果显示,术后妊娠组和未妊娠组患者的年龄、不孕年限、不孕类型、r-AFS分期、使用GnRH和促排卵治疗情况比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,年龄、不孕年限、不孕类型、r-AFS分期、使用GnRH和促排卵治疗情况是子宫内膜异位症并发不孕患者宫-腹腔镜联合治疗后不孕的独立危险因素(P<0.05)。结论年龄大、不孕年限长、r-AFS分期高是子宫内膜异位症并发不孕患者宫-腹腔镜联合治疗后不孕的危险因素,使用GnRH和促排卵治疗能提高患者的妊娠率。
ObjectiveTo investigate risk factors for infertility after treatment of hysteroscope combined with laparoscope on endometriosis complicated with infertility in order to improve postoperative pregnancy rate. MethodsA total of 98 cases of infertile patients with endometriosis admitted to our hospital from April 2013 to April 2014 were selected as the objects. The relative data of patients were collected by reviewing the medical records and 3 years follow-up results. According to the condition of postoperative pregnancy, patients were divided into pregnancy group (58 cases) and non-pregnancy group (40 cases). Through comparing the age, year of infertility, type of infertility, r-AFS stages, pathological type, condition of using GnRH, and ovulation treatment, meanwhile, using multivariate logistic regression analysis to explore risk factors for infertility after treatment of hysteroscopy combined with laparoscopy on endometriosis complicated with infertility. ResultsUnivariate analysis results revealed that the age, year of infertility, infertile type, r-AFS stages, condition of using GnRH and ovulation treatment were statistically significantly different between the pregnancy group and the non-pregnancy group after operation (P<0.05). Multivariate logistic regression analysis results showed that the age, year of infertility, infertile type, r-AFS stages, condition of using GnRH and ovulation treatment were independent risk factors for infertility after treatment of hysteroscope combined with laparoscope on endometriosis complicated with infertility (P<0.05). ConclusionThe advanced age, long infertility, and high stage of r-AFS are risk factors for infertility after treatment of hysteroscope combined with laparoscope on endometriosis complicated with infertility. Using GnRH and ovulation treatment can improve pregnancy rate of patients.