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冠心病患者BMI、VFA与其冠脉病变、hs-CRP、LDL-C水平的关系研究▲
Study on the relationship between BMI, VFA and coronary artery lesions, hs-CRP, LDL-C levels in patients with coronary heart disease

内科 202015卷01期 页码:5-7

作者机构:1 鹿邑县人民医院,河南省周口市477200;2 河南科技大学第一附属医院,河南省洛阳市471000

基金信息:▲基金项目:河南省医学科技攻关计划普通项目(201403258)

DOI:DOI:10.16121/j.cnki.cn45-1347/r.2020.01.02

  • 中文简介
  • 英文简介
  • 参考文献
目的探讨冠心病患者体质量指数(BMI)、内脏脂肪面积(VFA)与其冠脉病变、hs-CRP、LDL-C水平的关系。方法选取2017年1~12月在我院首次被确诊为冠心病并接受PCI手术治疗的患者300例为研究对象。对患者BMI 和VFA进行检测,根据BMI、VFA将患者分为超重腹胖组(88例)、超重非腹胖组(75例)、非超重腹胖组(66例)、非超重非腹胖组(71例)。检测比较4组患者心力衰竭、冠状动脉内膜重度增生发生情况以及血清超敏C反应蛋白(hs-CRP)和低密度脂蛋白胆固醇(LDL-C)水平。结果4组患者的心力衰竭、冠脉内膜重度增生发生率表现为非超重腹胖组>超重腹胖组>超重非腹胖组>非超重非腹胖组,但差异无统计学意义(P>0.05)。4组患者的血清hs-CRP水平比较差异无统计学意义(P>0.05);4组患者的血清LDL-C水平表现为非超重腹胖组>超重腹胖组>超重非腹胖组>非超重非腹胖组,差异有统计学意义(P<0.05)。结论冠心病患者的BMI、VFA与其病情的严重程度均无明显相关关系,肥胖或内脏脂肪面积较大的患者其低密度脂蛋白胆固醇水平显著升高。
ObjectiveTo investigate the relationship between body mass index (BMI), visceral fat area (VFA) and coronary artery lesions, hs-CRP, LDL-C levels in patients with coronary heart disease. MethodsA total of 300 patients first confirmed with coronary heart disease in our hospital from January to December 2017 and underwent PCI surgery were selected as the research subjects. Detection of BMI and VFA was performed on patients. According to BMI and VFA, patients were divided into overweight abdominal obese group (88 cases), overweight non-abdominal obese group (75 cases), non-overweight abdominal obese group (66 cases), non-overweight non-abdominal obese group (71 cases). The occurence of heart failure, severe hyperplasia of coronary intimal, and the levels of serum high-sensitivity C-reactive protein (hs-CRP) and low-density lipoprotein cholesterol (LDL-C) between the four groups were detected and compared. ResultsThe incidence of heart failure and severe hyperplasia of coronary intimal in the four groups in a descending order were non-overweight abdominal obese group, overweight abdominal obese group, overweight non-abdominal obese group and non-overweight non-abdominal obese group, but the differences were not statistically significant (P>0.05). There was no statistically significant difference in serum hs-CRP level between the four groups (P>0.05). The LDL-C level of the four groups in a descending order were non-overweight abdominal obese group, overweight abdominal obese group, overweight non-abdominal obese group and non-overweight non-abdominal obese group, with statistically significant difference (P<0.05). ConclusionThere is no significant correlation between BMI, VFA and the severity of disease. LDL-C level increases significantly in patients with obesity or larger VFA.

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