ObjectiveTo investigate the relationship between body mass index (BMI), visceral fat area (VFA) and coronary artery lesions, hs-CRP, LDL-C levels in patients with coronary heart disease. MethodsA total of 300 patients first confirmed with coronary heart disease in our hospital from January to December 2017 and underwent PCI surgery were selected as the research subjects. Detection of BMI and VFA was performed on patients. According to BMI and VFA, patients were divided into overweight abdominal obese group (88 cases), overweight non-abdominal obese group (75 cases), non-overweight abdominal obese group (66 cases), non-overweight non-abdominal obese group (71 cases). The occurence of heart failure, severe hyperplasia of coronary intimal, and the levels of serum high-sensitivity C-reactive protein (hs-CRP) and low-density lipoprotein cholesterol (LDL-C) between the four groups were detected and compared. ResultsThe incidence of heart failure and severe hyperplasia of coronary intimal in the four groups in a descending order were non-overweight abdominal obese group, overweight abdominal obese group, overweight non-abdominal obese group and non-overweight non-abdominal obese group, but the differences were not statistically significant (P>0.05). There was no statistically significant difference in serum hs-CRP level between the four groups (P>0.05). The LDL-C level of the four groups in a descending order were non-overweight abdominal obese group, overweight abdominal obese group, overweight non-abdominal obese group and non-overweight non-abdominal obese group, with statistically significant difference (P<0.05). ConclusionThere is no significant correlation between BMI, VFA and the severity of disease. LDL-C level increases significantly in patients with obesity or larger VFA.