ObjectiveTo investigate clinical effect of fat emulsion combined with magnesium sulfate in pregnant women with fetal growth restriction (FGR). MethodsA total of 160 pregnant women with FGR admitted to our hospital from February 2014 to January 2019 were selected as the research subjects and divided into observation group and control group according to the random number method, with 80 cases in each group. The control group was administered fat emulsion, whereas the observation group with fat emulsion combined with magnesium sulfate, with four-week continuous treatment for both groups. The pre- and post-treatment B-ultrasound umbilical blood flow status, uterine height of pregnant women, biparietal diameter and femur length of fetus were compared between the two groups. The efficacy and the occurrence of adverse reactions during treatment were compared between the two groups. ResultsBefore treatment, there were no statistically significant differences in umbilical blood flow ratio, uterine height, biparietal diameter and femur length of fetus between the two groups (P＞0.05). After 4 weeks of treatment, umbilical blood flow ratio, uterine height, biparietal diameter and femur length of fetus significantly increased. The levels of pregnant women and their fetuses in the observation group were significantly higher than those in the control group, with statistically significant differences (P＜0.05). The total effective rate of treatment in the observation group (96.3%) was significantly higher than that in the control group (85.0%), with statistically significant difference (P＜0.05). During treatment, there was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05). ConclusionFat emulsion combined with magnesium sulfate in the treatment of pregnant women with FGR is more effective to improve maternal and child health, and the treatment is highly safe, which is worthy of promotion and application.

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